Gpi Antibody, HRP conjugated
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中文名稱:Gpi兔多克隆抗體, HRP偶聯(lián)
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貨號(hào):CSB-PA009717LB01MO
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規(guī)格:¥880
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Mus musculus (Mouse) Gpi Polyclonal antibody
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Uniprot No.:
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基因名:Gpi
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別名:Gpi antibody; Gpi1Glucose-6-phosphate isomerase antibody; GPI antibody; EC 5.3.1.9 antibody; Autocrine motility factor antibody; AMF antibody; Neuroleukin antibody; NLK antibody; Phosphoglucose isomerase antibody; PGI antibody; Phosphohexose isomerase antibody; PHI antibody
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宿主:Rabbit
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反應(yīng)種屬:Mouse
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免疫原:Recombinant Mouse Glucose-6-phosphate isomerase protein (2-558AA)
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免疫原種屬:Mus musculus (Mouse)
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標(biāo)記方式:HRP
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion.
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基因功能參考文獻(xiàn):
- PGI is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor. PMID: 8674049
- The mGPI-transgenic mice presented GPI more efficiently and showed a dramatic increase in negative selection and an inhibition of arthritis. PMID: 23840022
- Data show that silencing of AMF/PGI induced MET and suppressed the tumor growth and pulmonary metastasis of LM8 cells in nude mice. PMID: 20978190
- induces hyperpermeability of endothelial and mesothelial cells leading to accumulation of ascites fluid (tumor autocrine motility factor) PMID: 12054583
- acid-induced conformational changes in phosphoglucose isomerase result in its increased cell surface association and deposition on fibronectin fibrils PMID: 12888574
- Gpi1 immunoreactivity was found in ganglion, amacrine, horizontal and bipolar cells, but not in rods, cones, pigment epithelium and Muller cells. PMID: 15182299
- High-resolution crystal structures of the enzyme from mouse have been determined in native form and in complex with the inhibitor erythrose 4-phosphate, and with the substrate glucose 6-phosphate. PMID: 15342241
- crystal structure of Autocrine Motility Factor PMID: 15502335
- AMF expression significantly contributes to the aggressive phenotype of pancreatic cancer PMID: 15570012
- Results report the first high-resolution crystal structure of the inhibitor-free form and the eight types of inhibitor complexes of mouse autocrine motility factor. PMID: 16375918
- the receptor molecule for AMF/NLK/MF in leukemic differentiation is not gp78 PMID: 17071500
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亞細(xì)胞定位:Cytoplasm. Secreted.
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蛋白家族:GPI family
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數(shù)據(jù)庫(kù)鏈接:
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