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TLR9

TLR9,即Toll樣受體9,別名CD288。它是一種由TLR9基因編碼的蛋白質(zhì),屬于Toll樣受體家族成員,在免疫系統(tǒng)的髓系細胞如樹突狀細胞、巨噬細胞和B細胞中表達。TLR9的作用機制涉及識別DNA病毒或細菌中的非甲基化CpG島,激活下游的MyD88依賴性信號通路,觸發(fā)免疫應(yīng)答。TLR9參與了機體對病原體的先天免疫反應(yīng),特別是對DNA病毒的識別和清除。TLR9的激活可以促進炎癥細胞因子的產(chǎn)生,增強樹突狀細胞的成熟和抗原呈遞能力,激活T細胞和B細胞,從而調(diào)節(jié)適應(yīng)性免疫反應(yīng)。TLR9是免疫學(xué)研究和相關(guān)疾病治療中的一個潛在靶點。

熱銷產(chǎn)品

TLR9 Antibody (CSB-PA023608LA01HU)

驗證數(shù)據(jù)

CSB-PA023608LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023608LA01HU at dilution of 1:100

CSB-PA023608LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA023608LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TLR9 Antibodies

TLR9 for Homo sapiens (Human)

TLR9 Proteins

TLR9 Proteins for Bos taurus (Bovine)

TLR9 Proteins for Felis catus (Cat) (Felis silvestris catus)

TLR9 Proteins for Sus scrofa (Pig)

TLR9 Proteins for Mus musculus (Mouse)

TLR9 Proteins for Homo sapiens (Human)

TLR9 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

TLR9 Proteins for Ovis aries (Sheep)

TLR9 ELISA Kit

TLR9 ELISA Kit for Homo sapiens (Human)