IL6

IL-6（白細(xì)胞介素-6）是一種糖蛋白，由184個氨基酸殘基組成，分子量約為21~26 kDa。它包含四個半胱氨酸殘基，形成兩個分子內(nèi)二硫鍵，這使得IL-6的結(jié)構(gòu)穩(wěn)定。IL-6的分泌形式可以是游離的，也可以與可溶性IL-6受體（sIL-6R）結(jié)合形成復(fù)合物。IL-6具有多種生物學(xué)功能，包括但不限于：免疫調(diào)節(jié)、炎癥反應(yīng)、造血作用：IL-6可以促進(jìn)骨髓造血干細(xì)胞的增殖和分化，參與紅細(xì)胞、血小板等血液成分的生成。IL-6與多種疾病的發(fā)生和發(fā)展密切相關(guān)，如風(fēng)濕性關(guān)節(jié)炎、多發(fā)性硬化癥、糖尿病、心血管疾病以及某些類型的腫瘤等。 IL-6的信號傳導(dǎo)主要通過以下兩種途徑實(shí)現(xiàn)：經(jīng)典信號通路：IL-6首先與膜結(jié)合的IL-6受體（mIL-6R）結(jié)合，然后招募并激活gp130分子（一個信號轉(zhuǎn)導(dǎo)蛋白）。激活的gp130觸發(fā)JAK（Janus激酶）的磷酸化，進(jìn)而激活STAT3（信號轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子3）?；罨腟TAT3進(jìn)入細(xì)胞核，調(diào)控基因表達(dá)。反式信號通路：在缺乏mIL-6R的細(xì)胞上，IL-6可以與sIL-6R結(jié)合，形成IL-6/sIL-6R復(fù)合物。這個復(fù)合物隨后與細(xì)胞表面的gp130結(jié)合并激活信號通路。這種反式信號通路使得IL-6能夠在更廣泛的細(xì)胞類型中發(fā)揮作用。異常的IL-6表達(dá)和信號傳導(dǎo)可能導(dǎo)致疾病的發(fā)生和發(fā)展。因此，對IL-6的深入研究有助于我們更好地理解其在疾病中的作用，并為疾病的治療提供新的思路和方法。

熱銷產(chǎn)品

IL6 Recombinant Monoclonal Antibody

驗(yàn)證數(shù)據(jù)

ELISA

The Binding Activity of Human IL6 with Anti-IL6 Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL6 (CSB-YP011664HU) at 2 μg/mL can bind Anti-IL6 recombinant antibody. The EC₅₀ is 35.80-41.82 ng/mL.

IL6 Antibody

IL6 Protein

IL6 ELISA Kit

IL6 Antibodies

IL6 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA06757B0Rb	IL6 Antibody, HRP conjugated	Human	ELISA
CSB-PA06757C0Rb	IL6 Antibody, FITC conjugated	Human
CSB-PA06757A0Rb	IL6 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA06757D0Rb	IL6 Antibody, Biotin conjugated	Human	ELISA
CSB-PA005546	IL6 Antibody	Human	WB, ELISA
CSB-RA011664MA1HU	IL6 Recombinant Monoclonal Antibody	Human	ELISA

IL6 Proteins

IL6 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664BO CSB-BP011664BO CSB-MP011664BO CSB-EP011664BO-B	Recombinant Bovine Interleukin-6 (IL6)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664DO CSB-EP011664DO CSB-BP011664DO CSB-MP011664DO CSB-EP011664DO-B	Recombinant Dog Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664PI CSB-EP011664PI CSB-BP011664PI CSB-MP011664PI CSB-EP011664PI-B	Recombinant Pig Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664SH	Recombinant Sheep Interleukin-6 (IL6)	Yeast
CSB-EP011664SH	Recombinant Sheep Interleukin-6 (IL6)	E.coli
CSB-BP011664SH CSB-MP011664SH CSB-EP011664SH-B	Recombinant Sheep Interleukin-6 (IL6)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Felis catus (Cat) (Felis silvestris catus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664CA CSB-EP011664CA CSB-BP011664CA CSB-MP011664CA CSB-EP011664CA-B	Recombinant Cat Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Macaca mulatta (Rhesus macaque)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664MOW CSB-EP011664MOW CSB-BP011664MOW CSB-MP011664MOW CSB-EP011664MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003101MOW	Recombinant Macaca mulatta Interleukin-6 protein (IL6)	E.Coli

IL6 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-BP011664HU CSB-MP011664HU CSB-EP011664HU-B	Recombinant Human Interleukin-6 (IL6)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001741HU	Recombinant Human Interleukin-6 protein (IL6)	E.Coli
CSB-EP011664HU	Recombinant Human Interleukin-6 (IL6),Escherichia Coli	E.coli
CSB-AP004301HU	Recombinant Human Interleukin-6 (IL6) (Active)	E.coli
CSB-AP005841HU	Recombinant Human Interleukin-6 (IL6) (Active) (GMP)	E.Coli
CSB-YP011664HU	Recombinant Human Interleukin-6(IL6) (Active)	yeast
CSB-MP011664HU-B	Recombinant Human Interleukin-6 (IL6), Biotinylated	Mammalian cell

IL6 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP011664MO CSB-EP011664MO CSB-BP011664MO CSB-MP011664MO CSB-EP011664MO-B	Recombinant Mouse Interleukin-6 (Il6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003321MO	Recombinant Mouse Interleukin-6 protein (Il6) (Active)	E.Coli

IL6 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP305249MOV CSB-EP305249MOV CSB-BP305249MOV CSB-MP305249MOV CSB-EP305249MOV-B	Recombinant Macaca fascicularis Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP322670RA CSB-EP322670RA CSB-BP322670RA CSB-MP322670RA CSB-EP322670RA-B	Recombinant Rat Interleukin-6 (Il6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Mustela vison (American mink) (Neovison vison)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP336891MVE CSB-EP336891MVE CSB-BP336891MVE CSB-MP336891MVE CSB-EP336891MVE-B	Recombinant Mustela vison Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP342020DRI CSB-EP342020DRI CSB-BP342020DRI CSB-MP342020DRI CSB-EP342020DRI-B	Recombinant Cercocebus atys Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP385261MOH CSB-EP385261MOH CSB-BP385261MOH CSB-MP385261MOH CSB-EP385261MOH-B	Recombinant Mustela putorius furo Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Sparus aurata (Gilthead sea bream)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP466936FJX CSB-EP466936FJX CSB-BP466936FJX CSB-MP466936FJX CSB-EP466936FJX-B	Recombinant Sparus aurata Interleukin-6 (il6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Marmota monax (Woodchuck)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP518577MQG CSB-EP518577MQG CSB-BP518577MQG CSB-MP518577MQG CSB-EP518577MQG-B	Recombinant Marmota monax Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP610956OEI CSB-EP610956OEI CSB-BP610956OEI CSB-MP610956OEI CSB-EP610956OEI-B	Recombinant Oncorhynchus mykiss Interleukin-6 (il6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Orcinus orca (Killer whale)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP630696OEP CSB-EP630696OEP CSB-BP630696OEP CSB-MP630696OEP CSB-EP630696OEP-B	Recombinant Orcinus orca Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Capra hircus (Goat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP631708GO CSB-EP631708GO CSB-BP631708GO CSB-MP631708GO CSB-EP631708GO-B	Recombinant Goat Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Phoca vitulina (Harbor seal)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP631730EUR CSB-EP631730EUR CSB-BP631730EUR CSB-MP631730EUR CSB-EP631730EUR-B	Recombinant Phoca vitulina Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Vulpes vulpes (Red fox)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP635622VFW CSB-EP635622VFW CSB-BP635622VFW CSB-MP635622VFW CSB-EP635622VFW-B	Recombinant Vulpes vulpes Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP640800BAAW CSB-EP640800BAAW CSB-BP640800BAAW CSB-MP640800BAAW CSB-EP640800BAAW-B	Recombinant Bubalus carabanensis Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Macaca thibetana (Pere David's macaque) (Tibetan macaque)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP686313MDAO CSB-EP686313MDAO CSB-BP686313MDAO CSB-MP686313MDAO CSB-EP686313MDAO-B	Recombinant Macaca thibetana Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Bubalus bubalis (Domestic water buffalo)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP740930BWX CSB-EP740930BWX CSB-BP740930BWX CSB-MP740930BWX CSB-EP740930BWX-B	Recombinant Bubalus bubalis Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP760907TKY CSB-EP760907TKY CSB-BP760907TKY CSB-MP760907TKY CSB-EP760907TKY-B	Recombinant Takifugu rubripes Interleukin-6 (il6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Camelus bactrianus (Bactrian camel)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP772948CVZ CSB-EP772948CVZ CSB-BP772948CVZ CSB-MP772948CVZ CSB-EP772948CVZ-B	Recombinant Camelus bactrianus Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Lama glama (Llama)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP803040LBS CSB-BP803040LBS CSB-EP803040LBS-B	Recombinant Lama glama Interleukin-6 (IL6)	Yeast Baculovirus In Vivo Biotinylation in E.coli

IL6 Proteins for Saimiri sciureus (Common squirrel monkey)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP847583SWD CSB-EP847583SWD CSB-BP847583SWD CSB-MP847583SWD CSB-EP847583SWD-B	Recombinant Saimiri sciureus Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP856206CH CSB-EP856206CH CSB-BP856206CH CSB-MP856206CH CSB-EP856206CH-B	Recombinant Chicken Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Equus caballus (Horse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP856767HO CSB-EP856767HO CSB-BP856767HO CSB-MP856767HO CSB-EP856767HO-B	Recombinant Horse Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP863071RB	Recombinant Rabbit Interleukin-6 (IL6)	Yeast
CSB-EP863071RB CSB-BP863071RB CSB-MP863071RB CSB-EP863071RB-B	Recombinant Rabbit Interleukin-6 (IL6)	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 Proteins for Delphinapterus leucas (Beluga whale)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP893174DJB CSB-EP893174DJB CSB-BP893174DJB CSB-MP893174DJB CSB-EP893174DJB-B	Recombinant Delphinapterus leucas Interleukin-6 (IL6)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL6 ELISA Kit

IL6 ELISA Kit for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E12899B	Bovine Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	2.5 pg/mL

IL6 ELISA Kit for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E08549Ch	Chicken Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	3.9 pg/mL

IL6 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E11260c	Dog Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	0.39 pg/mL

IL6 ELISA Kit for Capra hircus (Goat)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E14360G	Goat Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	0.39 pg/mL

IL6 ELISA Kit for Monkey

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E10050Mo	Monkey Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	7.8 pg/mL

IL6 ELISA Kit for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E04639m	Mouse Interleukin 6,IL-6 ELISA KIT

IL6 ELISA Kit for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E06786p	Pig Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	0.31 pg/mL

IL6 ELISA Kit for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E06903Rb	Rabbit Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	3.9 pg/mL

IL6 ELISA Kit for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E04640r	Rat Interleukin 6,IL-6 ELISA KIT	serum, plasma, tissue homogenates	0.078 pg/ml

IL6 ELISA Kit for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E10116Sh	Sheep Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	2 pg/mL

IL6 ELISA Kit for Fish

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E13258Fh	Fish Interleukin 6,IL-6 ELISA Kit	serum, plasma, tissue homogenates	12.5 pg/mL

IL6 ELISA Kit for Equus caballus (Horse)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E16634Hs	Horse Interleukin 6(IL-6)ELISA Kit	serum, plasma, tissue homogenates	0.78 pg/mL

IL6 ELISA Kit for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	樣本類型	靈敏度
CSB-E04638h	Human Interleukin 6,IL-6 ELISA KIT	serum, plasma, cell culture supernates, tissue homogenates, urine	2.453 pg/mL

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