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TNFSF13B

TNFSF13B,即腫瘤壞死因子超家族成員13B,別名BLyS、BAFF、TALL-1。它是一種主要由B細胞產(chǎn)生的細胞因子,屬于腫瘤壞死因子超家族成員,在B細胞的成熟和存活中發(fā)揮關(guān)鍵作用。TNFSF13B的作用機制涉及與其受體BAFF-R結(jié)合,激活下游的信號傳導(dǎo)途徑,如NF-κB和JAK/STAT通路,促進B細胞的增殖和分化。TNFSF13B在生物學(xué)上的意義非常廣泛,它參與了B細胞的發(fā)育、自身免疫性疾病的發(fā)生以及腫瘤的生長。TNFSF13B的異常表達與某些B細胞相關(guān)疾病,如系統(tǒng)性紅斑狼瘡、類風(fēng)濕關(guān)節(jié)炎和某些類型的非霍奇金淋巴瘤有關(guān),使其成為治療這些疾病的潛在靶點。

熱銷產(chǎn)品

Recombinant Human Tumor necrosis factor ligand superfamily member 13B protein (TNFSF13B), partial (CSB-EP897523HU)

驗證數(shù)據(jù)

CSB-EP897523HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TNFSF13B Antibody (CSB-PA981923)

驗證數(shù)據(jù)

CSB-PA981923

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA981923

The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA981923(TNFSF13B Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA981923

Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: K562 cells, 231 cells, SKOV3 cells, Primary antibody: CSB-PA981923(TNFSF13B Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

TNFSF13B Antibodies

TNFSF13B for Homo sapiens (Human)

TNFSF13B Proteins

TNFSF13B Proteins for Mus musculus (Mouse)

TNFSF13B Proteins for Homo sapiens (Human)

TNFSF13B ELISA Kit

TNFSF13B ELISA Kit for Homo sapiens (Human)