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TNFSF11

TNFSF11,即腫瘤壞死因子超家族成員11,別名OPGL、RANKL、TRANCE,是一種關(guān)鍵的細(xì)胞因子,在骨代謝、免疫系統(tǒng)和腫瘤生物學(xué)中扮演重要角色。由T細(xì)胞產(chǎn)生,TNFSF11通過與其受體RANK結(jié)合,激活NF-κB信號(hào)通路,促進(jìn)破骨細(xì)胞的分化和活性,影響骨吸收。異常的TNFSF11表達(dá)與骨質(zhì)疏松癥、骨轉(zhuǎn)移癌等疾病有關(guān),同時(shí)在腫瘤微環(huán)境中可能促進(jìn)腫瘤細(xì)胞的侵襲和轉(zhuǎn)移,使其成為治療相關(guān)疾病的潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11), partial (CSB-MP023986HU(F2))

驗(yàn)證數(shù)據(jù)

CSB-MP023986HU(F2)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TNFSF11 Antibody (CSB-PA023986LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA023986LA01HU

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA023986LA01HU at dilution of 1:100

CSB-PA023986LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023986LA01HU at dilution of 1:100

CSB-PA023986LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA023986LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TNFSF11 Antibodies

TNFSF11 for Mus musculus (Mouse)

TNFSF11 for Homo sapiens (Human)

TNFSF11 Proteins

TNFSF11 Proteins for Mus musculus (Mouse)

TNFSF11 Proteins for Homo sapiens (Human)

TNFSF11 Proteins for Rattus norvegicus (Rat)

TNFSF11 ELISA Kit

TNFSF11 ELISA Kit for Homo sapiens (Human)

TNFSF11 ELISA Kit for Mus musculus (Mouse)

TNFSF11 ELISA Kit for Rattus norvegicus (Rat)