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TGFBR2

TGFBR2,即轉(zhuǎn)化生長因子β受體2,別名TGFβR-II、TGFβRII。它是一種跨膜蛋白,由TGFBR2基因編碼,主要在細(xì)胞表面發(fā)揮作用。TGFBR2的作用機(jī)制涉及與轉(zhuǎn)化生長因子β(TGF-β)家族配體結(jié)合,激活其內(nèi)在的絲氨酸/蘇氨酸激酶活性,進(jìn)而磷酸化并激活Smad蛋白,這些Smad蛋白隨后轉(zhuǎn)移到細(xì)胞核,調(diào)控下游基因的表達(dá)。TGFBR2在細(xì)胞增殖、分化、遷移和凋亡等過程中發(fā)揮關(guān)鍵作用,影響組織發(fā)育、免疫調(diào)節(jié)、纖維化和腫瘤發(fā)展等生物學(xué)過程。

熱銷產(chǎn)品

Recombinant Human TGF-beta receptor type-2 (TGFBR2), partial (CSB-EP023452HU1)

驗證數(shù)據(jù)

CSB-EP023452HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFBR2 Antibody (CSB-PA023452LA01HU)

驗證數(shù)據(jù)

CSB-PA023452LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023452LA01HU at dilution of 1:100

CSB-PA023452LA01HU

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA023452LA01HU at dilution of 1:100

CSB-PA023452LA01HU

Immunofluorescent analysis of MCF-7 cells using CSB-PA023452LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TGFBR2 Antibodies

TGFBR2 for Homo sapiens (Human)

TGFBR2 Proteins

TGFBR2 Proteins for Rattus norvegicus (Rat)

TGFBR2 Proteins for Sus scrofa (Pig)

TGFBR2 Proteins for Mus musculus (Mouse)

TGFBR2 Proteins for Gallus gallus (Chicken)

TGFBR2 Proteins for Homo sapiens (Human)

TGFBR2 ELISA Kit

TGFBR2 ELISA Kit for Homo sapiens (Human)