SOD1
SOD1，即銅鋅超氧化物歧化酶（Cu/Zn superoxide dismutase），是一種具有關(guān)鍵抗氧化功能的酶，其結(jié)構(gòu)特征在于含有銅和鋅離子輔基。功能上，SOD1通過(guò)催化超氧陰離子歧化為氧氣和過(guò)氧化氫，維持細(xì)胞內(nèi)活性氧的平衡，從而保護(hù)細(xì)胞免受氧化應(yīng)激損傷。在信號(hào)通路方面，SOD1通過(guò)調(diào)節(jié)胞內(nèi)活性氧水平，影響細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)過(guò)程，包括激活NF-κB、AP-1以及JAK-STAT等信號(hào)通路，這些通路與細(xì)胞增殖、凋亡和炎癥反應(yīng)等密切相關(guān)。此外，SOD1的異常表達(dá)與神經(jīng)系統(tǒng)疾病如肌萎縮側(cè)索硬化癥（ALS）的發(fā)病過(guò)程緊密相關(guān)。
熱銷(xiāo)產(chǎn)品
SOD1 Recombinant Monoclonal Antibody
驗(yàn)證數(shù)據(jù)
Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
All lanes: SOD1 antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 16 kDa
Observed band size: 18 kDa
Overlay histogram showing Jurkat cells stained with CSB-RA829583A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
SOD1 Antibodies
SOD1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA02864D0Rb | SOD1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA02864B0Rb | SOD1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA022397GA01HU | SOD1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA02864C0Rb | SOD1 Antibody, FITC conjugated | Human | |
| CSB-PA02864A0Rb | SOD1 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA004131 | SOD1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA080200 | SOD1 Antibody | Human,Mouse,Rat | WB, IHC |
| CSB-PA238446 | SOD1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-RA829583A0HU | SOD1 Recombinant Monoclonal Antibody | Human | ELISA, WB, FC |
| CSB-RA022397MA1HU | SOD1 Recombinant Monoclonal Antibody | Human | ELISA, IF, FC |
SOD1 Proteins
SOD1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP022397HU CSB-EP022397HU CSB-BP022397HU CSB-MP022397HU CSB-EP022397HU-B |
Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000121HU | Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1) (Active) | E.Coli |
| CSB-AP000131HU | Recombinant Human Superoxide dismutase [Cu-Zn] protein (SOD1) | E.Coli |
SOD1 ELISA Kit
SOD1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E16845h | Human Superoxide dismutase [Cu-Zn] (SOD1) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/ml |
