SLC34A2
SLC34A2,即溶質(zhì)載體家族34成員A2,別名鈉-磷共運(yùn)輸?shù)鞍?”(NaPi2)/腎磷酸鹽重吸收蛋白等。SLC34A2是一種在細(xì)胞膜上表達(dá)的跨膜蛋白,屬于SLC34家族成員,主要在腎臟、小腸和某些腫瘤細(xì)胞中發(fā)揮作用。其作用機(jī)制涉及鈉依賴性磷酸鹽轉(zhuǎn)運(yùn),通過(guò)與鈉離子的協(xié)同運(yùn)輸,促進(jìn)磷酸鹽從尿液或腸腔重吸收到血液中。SLC34A2的活性受多種因素調(diào)節(jié),包括pH值、細(xì)胞外磷酸鹽和鈉離子濃度等,這種調(diào)節(jié)作用對(duì)維持體內(nèi)磷酸鹽平衡至關(guān)重要。SLC34A2在生物學(xué)上的意義主要體現(xiàn)在其對(duì)磷酸鹽穩(wěn)態(tài)的調(diào)控上。它參與了體內(nèi)磷酸鹽的吸收和重吸收過(guò)程,對(duì)骨骼健康、細(xì)胞信號(hào)傳導(dǎo)、能量代謝等具有重要影響。SLC34A2的功能異常與低磷血癥、佝僂病、骨軟化癥等磷酸鹽代謝紊亂疾病有關(guān)。此外,SLC34A2在腫瘤微環(huán)境中的表達(dá)可能與腫瘤的侵襲性和轉(zhuǎn)移能力有關(guān),因此,它也是癌癥研究和治療中的潛在靶點(diǎn)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SLC34A2 Antibody (CSB-PA140842)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA140842(SLC34A2 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA140842(SLC34A2 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
SLC34A2 Antibodies
SLC34A2 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA004755 | SLC34A2 Antibody | Human,Rat | WB, ELISA |
CSB-PA140842 | SLC34A2 Antibody | Human | ELISA,IHC |
CSB-PA968633 | SLC34A2 Antibody | Human | ELISA,IHC |
CSB-PA021581LA01HU | SLC34A2 Antibody | Human | ELISA, IHC |
CSB-PA021581LB01HU | SLC34A2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA021581LD01HU | SLC34A2 Antibody, Biotin conjugated | Human | ELISA |
SLC34A2 Proteins
SLC34A2 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP021581HU | Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2), partial | Yeast |
CSB-EP021581HU | Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2), partial | E.coli |
CSB-BP021581HU CSB-MP021581HU CSB-EP021581HU-B |
Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC34A2 Proteins for Bos taurus (Bovine)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP631682BO CSB-EP631682BO CSB-BP631682BO CSB-MP631682BO CSB-EP631682BO-B |
Recombinant Bovine Sodium-dependent phosphate transport protein 2B (SLC34A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC34A2 Proteins for Pongo abelii (Sumatran orangutan)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP716226PYX CSB-EP716226PYX CSB-BP716226PYX CSB-MP716226PYX CSB-EP716226PYX-B |
Recombinant Pongo abelii Sodium-dependent phosphate transport protein 2B (SLC34A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC34A2 Proteins for Rattus norvegicus (Rat)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP872848RA CSB-EP872848RA CSB-BP872848RA CSB-MP872848RA CSB-EP872848RA-B |
Recombinant Rat Sodium-dependent phosphate transport protein 2B (Slc34a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC34A2 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP887584MO CSB-EP887584MO CSB-BP887584MO CSB-MP887584MO CSB-EP887584MO-B |
Recombinant Mouse Sodium-dependent phosphate transport protein 2B (Slc34a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |