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NCL

NCL蛋白(Nucleolin)是一種廣泛存在于細(xì)胞核中的蛋白質(zhì),它與核仁內(nèi)染色質(zhì)和前核糖體顆粒有關(guān),通過與組蛋白 H1 結(jié)合誘導(dǎo)染色質(zhì)解縮。它被認(rèn)為在 rRNA 前體轉(zhuǎn)錄和核糖體組裝中發(fā)揮作用,也可能在轉(zhuǎn)錄延伸過程中發(fā)揮作用。NCL在細(xì)胞核中參與多種生物學(xué)過程,包括:核糖體生物合成、基因表達(dá)調(diào)控、細(xì)胞增殖和生長:NCL參與細(xì)胞的增殖和生長,可能與細(xì)胞周期的調(diào)控有關(guān)、信號(hào)傳導(dǎo)等。該蛋白因其在細(xì)胞核中的多功能性而備受關(guān)注可能因?yàn)樵诩?xì)胞功能和疾病中的作用作為治療策略的潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Nucleolin (NCL), partial

驗(yàn)證數(shù)據(jù)

SDS-PAGE
CSB-YP015535HU-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS
CSB-YP015535HU LC-MS-1

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP015535HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) NCL.

LC-MS
CSB-YP015535HU LC-MS-2

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP015535HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) NCL.


NCL Antibodies

NCL for Homo sapiens (Human)

NCL Proteins

NCL Proteins for Rattus norvegicus (Rat)

NCL Proteins for Homo sapiens (Human)

NCL Proteins for Gallus gallus (Chicken)

NCL Proteins for Mus musculus (Mouse)

NCL Proteins for Xenopus laevis (African clawed frog)

NCL Proteins for Mesocricetus auratus (Golden hamster)

NCL Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

NCL Proteins for Pongo abelii (Sumatran orangutan)

NCL ELISA Kit

NCL ELISA Kit for Homo sapiens (Human)