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NCAM1

NCAM1,即神經(jīng)細(xì)胞黏附分子1,別名CD56、N-CAM等。它是一種由NCAM1基因編碼的細(xì)胞表面糖蛋白,屬于免疫球蛋白超家族成員,在神經(jīng)系統(tǒng)和免疫系統(tǒng)的多種細(xì)胞中表達(dá)。NCAM1的作用機(jī)制涉及同型和異型細(xì)胞黏附,通過(guò)同源或異源結(jié)合促進(jìn)細(xì)胞間的相互作用,參與神經(jīng)發(fā)育、突觸可塑性和細(xì)胞遷移。NCAM1參與了神經(jīng)系統(tǒng)的發(fā)育和維持,與腫瘤細(xì)胞的黏附、侵襲和轉(zhuǎn)移能力有關(guān)。NCAM1的功能異常與某些神經(jīng)系統(tǒng)疾病如阿爾茨海默病、精神分裂癥等有關(guān),同時(shí)在腫瘤發(fā)展中也發(fā)揮作用,是腫瘤治療中的潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Neural cell adhesion molecule 1 (NCAM1), partial (CSB-EP015511HU1)

驗(yàn)證數(shù)據(jù)

CSB-EP015511HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NCAM1 Antibody (CSB-PA087056)

驗(yàn)證數(shù)據(jù)

CSB-PA087056

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA087056(NCAM1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA087056

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA087056(NCAM1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA087056

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA087056(NCAM1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds

NCAM1 Antibodies

NCAM1 for Homo sapiens (Human)

NCAM1 Proteins

NCAM1 Proteins for Rattus norvegicus (Rat)

NCAM1 Proteins for Gallus gallus (Chicken)

NCAM1 Proteins for Mus musculus (Mouse)

NCAM1 Proteins for Homo sapiens (Human)

NCAM1 Proteins for Bos taurus (Bovine)

NCAM1 ELISA Kit

NCAM1 ELISA Kit for Homo sapiens (Human)