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MYL12A

MYL12A,也被稱為肌球蛋白輕鏈12A,其編碼的蛋白質(zhì)是非肌節(jié)性肌球蛋白調(diào)節(jié)輕鏈。這種蛋白質(zhì)在平滑肌和非肌肉細(xì)胞收縮過程中起到關(guān)鍵作用,其磷酸化狀態(tài)可以影響肌動(dòng)蛋白復(fù)合物的活性,從而調(diào)節(jié)肌肉收縮強(qiáng)度、細(xì)胞運(yùn)動(dòng)速度等。因此,MYL12A在肌肉收縮運(yùn)動(dòng)、細(xì)胞分裂等多種生命活動(dòng)中發(fā)揮重要作用。 此外,近期研究發(fā)現(xiàn),MYL12A在多種疾病中扮演重要角色。其磷酸化水平與心臟疾?。ㄈ缧募p傷、心肌肥厚)和癌癥相關(guān),因此,MYL12A有望作為心臟、腫瘤等多種疾病的研究潛力靶點(diǎn),成為重要的生物學(xué)標(biāo)志物。

熱銷產(chǎn)品

Recombinant Human Myosin regulatory light chain 12A (MYL12A) (Active)

驗(yàn)證數(shù)據(jù)

SDS
CSB-EP015307HUc7 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-EP015307HUc7 ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human MYL12A at 2μg/mL can bind Anti-MYL9 recombinant antibody (CSB-RA015318MA1HU),the EC50 is 5.325-6.456 ng/mL.


MYL12A Proteins

MYL12A Proteins for Homo sapiens (Human)

MYL12A Proteins for Pongo abelii (Sumatran orangutan)