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MET

MET,即肝細胞生長因子受體,別名c-Met。它起源于肝細胞生長因子(HGF)的發(fā)現(xiàn),是HGF的唯一高親和力受體。作用機制上,MET通過與HGF結(jié)合,激活其酪氨酸激酶活性,進而促進細胞增殖、遷移和分化。MET在胚胎發(fā)育、組織再生和傷口愈合中發(fā)揮重要作用,同時也是腫瘤發(fā)生發(fā)展的關(guān)鍵因子,其異常激活與多種癌癥相關(guān)。

熱銷產(chǎn)品

Recombinant Human Hepatocyte growth factor receptor (MET), partial (Active) (CSB-MP013714HU)

驗證數(shù)據(jù)

CSB-MP013714HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP013714HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized MET at 2 μg/ml can bind Anti-MET recombinant antibody, the EC50 is 2.379-3.094 ng/ml.

MET Recombinant Monoclonal Antibody (CSB-RA634199A0HU)

驗證數(shù)據(jù)

CSB-RA634199A0HU

IHC image of CSB-RA634199A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA634199A0HU

IHC image of CSB-RA634199A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

MET Antibodies

MET for Homo sapiens (Human)

MET Proteins

MET Proteins for Mus musculus (Mouse)

MET Proteins for Homo sapiens (Human)

MET Proteins for Felis catus (Cat) (Felis silvestris catus)

MET Proteins for Rattus norvegicus (Rat)

MET Proteins for Papio anubis (Olive baboon)

MET Proteins for Echinops telfairi (Lesser hedgehog tenrec)

MET Proteins for Ovis aries (Sheep)

MET Proteins for Loxodonta africana (African elephant)

MET Proteins for Rhinolophus ferrumequinum (Greater horseshoe bat)

MET Proteins for Pongo abelii (Sumatran orangutan)

MET Proteins for Gorilla gorilla gorilla (Lowland gorilla)

MET Proteins for Eulemur macaco macaco (Black lemur)

MET Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

MET Proteins for Microcebus murinus (Lesser mouse lemur)

MET Proteins for Callicebus moloch (Dusky titi monkey)

MET Proteins for Pan troglodytes (Chimpanzee)

MET Proteins for Equus caballus (Horse)

MET Proteins for Sus scrofa (Pig)

MET Proteins for Callithrix jacchus (White-tufted-ear marmoset)

MET Proteins for Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)

MET Proteins for Solenostemon scutellarioides (Coleus) (Coleus blumei)

MET Proteins for Bos taurus (Bovine)

MET Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

MET ELISA Kit

MET ELISA Kit for Homo sapiens (Human)

MET ELISA Kit for Mus musculus (Mouse)