MERTK
MERTK（Mer Tyrosine Kinase）是一種酪氨酸激酶受體，屬于Tyro3-Axl-Mer（TAM）家族。MERTK在細(xì)胞信號(hào)傳導(dǎo)和免疫系統(tǒng)中發(fā)揮著關(guān)鍵作用，特別是在吞噬細(xì)胞（例如巨噬細(xì)胞）的功能和調(diào)節(jié)中起著重要作用。 MERTK在免疫系統(tǒng)中也有一定的作用，尤其是在調(diào)節(jié)免疫細(xì)胞的活化和功能方面。它可以影響免疫細(xì)胞的調(diào)控，以維持免疫平衡。異常的MERTK信號(hào)傳導(dǎo)與一些疾病和疾病狀態(tài)相關(guān)，例如自身免疫疾病、炎癥性疾病和癌癥。因此，MERTK已被認(rèn)為是一種潛在的治療靶點(diǎn)。一些藥物和治療方法正在研究中，以干預(yù)MERTK信號(hào)傳導(dǎo)以治療相關(guān)疾病。
熱銷產(chǎn)品
● Recombinant Human Tyrosine-protein kinase Mer(MERTK),partial (Active) CSB-MP621519HU
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized MERTK at 2 μg/ml can bind anti-MERTK antibody（CSB-RA621519A1HU）, the EC50 is 32.95-48.25 ng/mL.
● Recombinant Mouse Tyrosine-protein kinase Mer(Mertk),partial (Active) CSB-MP723346MO
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Mertk at 2 μg/ml can bind anti-MERTK recombinant antibody（CSB-RA621519A1HU）, the EC50 is 19.22-25.80 ng/mL.
● MERTK Recombinant Monoclonal Antibody CSB-RA621519A1HU
驗(yàn)證數(shù)據(jù)
The Binding Activity of MERTK with anti-MERTK antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized MERTK at 2 μg/mL can bind anti-MERTK antibody(CSB-RA621519A1HU), the EC50 is 41.31-72.08 ng/mL.
MERTK Antibodies
MERTK for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA253602 | MERTK Antibody | Human | ELISA,WB |
| CSB-PA621519ESR1HU | MERTK Antibody | Human, Mouse | ELISA, WB |
| CSB-PA621519ESR2HU | MERTK Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA003228 | MERTK Antibody | Human | WB, ELISA |
| CSB-PA999740 | MERTK Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA668039 | MERTK Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA621519A1HU | MERTK Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-MA621519A0m | MERTK Monoclonal Antibody | Human | ELISA, WB, IHC, IF, FC |
MERTK Proteins
MERTK Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013706RA CSB-EP013706RA CSB-BP013706RA CSB-EP013706RA-B |
Recombinant Rat Tyrosine-protein kinase Mer (Mertk), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP013706RA | Recombinant Rat Tyrosine-protein kinase Mer (Mertk), partial | Mammalian cell |
MERTK Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP621519HU CSB-EP621519HU CSB-BP621519HU CSB-EP621519HU-B |
Recombinant Human Tyrosine-protein kinase Mer (MERTK), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP621519HU | Recombinant Human Tyrosine-protein kinase Mer (MERTK), partial (Active) | Mammalian cell |
MERTK Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723346MO1 CSB-EP723346MO CSB-BP723346MO CSB-EP723346MO1-B |
Recombinant Mouse Tyrosine-protein kinase Mer (Mertk), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP723346MO | Recombinant Mouse Tyrosine-protein kinase Mer (Mertk), partial (Active) | Mammalian cell |
