KITLG

KITLG，即激酶插入域受體配體，別名干細(xì)胞因子（Stem Cell Factor, SCF）、鋼因子（Steel Factor）、c-Kit配體等。它是一種由KITLG基因編碼的細(xì)胞因子，主要在多種細(xì)胞類型中表達(dá)，包括干細(xì)胞、肥大細(xì)胞和黑色素細(xì)胞等。KITLG的作用機(jī)制主要是通過與其受體c-Kit結(jié)合，激活下游的信號(hào)傳導(dǎo)途徑，如PI3K-AKT、RAS-MAPK、JAK-STAT等，從而促進(jìn)細(xì)胞的增殖、分化、存活和遷移。在生物學(xué)意義上，KITLG對維持組織穩(wěn)態(tài)、傷口愈合及免疫反應(yīng)等過程具有重要意義。它在胚胎發(fā)育、造血、性腺發(fā)育、黑素生成等過程中發(fā)揮重要作用。此外，KITLG還參與調(diào)節(jié)肥大細(xì)胞的粘附、遷移、增殖和存活，以及組胺和類胰蛋白酶的釋放，這些過程在過敏反應(yīng)中起作用。異常的KITLG表達(dá)或功能失調(diào)與某些類型的癌癥（如胃腸道間質(zhì)瘤GIST）和一些遺傳性皮膚病有關(guān)，例如家族性進(jìn)行性高色素沉著癥（Familial Progressive Hyperpigmentation, FPHH）。

熱銷產(chǎn)品

Recombinant Human Kit ligand (KITLG), partial (CSB-MP002061HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

KITLG Antibody (CSB-PA012376ESR2HU)

驗(yàn)證數(shù)據(jù)

Western blot
All lanes: Kit ligand antibody at 4μg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31, 28, 27 kDa
Observed band size: 31 kDa

KITLG Antibody

KITLG Protein

KITLG ELISA Kit

KITLG Antibodies

KITLG for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA012376ESR2HU	KITLG Antibody	Human	ELISA, WB
CSB-PA122514	KITLG Antibody	Human	ELISA,WB

KITLG Proteins

KITLG Proteins for Ovis aries (Sheep)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376SH1 CSB-EP012376SH1 CSB-BP012376SH1 CSB-MP012376SH1 CSB-EP012376SH1-B	Recombinant Sheep Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376SH	Recombinant Sheep Kit ligand (KITLG)	in vitro E.coli expression system

KITLG Proteins for Felis catus (Cat) (Felis silvestris catus)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376CA1 CSB-EP012376CA1 CSB-BP012376CA1 CSB-MP012376CA1 CSB-EP012376CA1-B	Recombinant Cat Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376CA	Recombinant Cat Kit ligand (KITLG)	in vitro E.coli expression system

KITLG Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376RA1 CSB-EP012376RA1 CSB-BP012376RA1 CSB-MP012376RA1 CSB-EP012376RA1-B	Recombinant Rat Kit ligand (Kitlg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376RA	Recombinant Rat Kit ligand (Kitlg)	in vitro E.coli expression system

KITLG Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376MO1 CSB-EP012376MO1 CSB-BP012376MO1 CSB-MP012376MO1 CSB-EP012376MO1-B	Recombinant Mouse Kit ligand (Kitlg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003151MO	Recombinant Mouse Kit ligand protein (Kitlg), partial (Active)	E.Coli
CSB-CF012376MO	Recombinant Mouse Kit ligand (Kitlg)	in vitro E.coli expression system
CSB-AP004071MO	Recombinant Mouse Kit ligand (Kitlg), partial (Active)	E.coli

KITLG Proteins for Mustela vison (American mink) (Neovison vison)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376MVE CSB-EP012376MVE CSB-BP012376MVE CSB-MP012376MVE CSB-EP012376MVE-B	Recombinant Mustela vison Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376DXJ CSB-EP012376DXJ CSB-BP012376DXJ CSB-MP012376DXJ CSB-EP012376DXJ-B	Recombinant Coturnix coturnix japonica Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Capra hircus (Goat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376GO CSB-EP012376GO CSB-BP012376GO CSB-MP012376GO CSB-EP012376GO-B	Recombinant Goat Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Equus caballus (Horse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376HO CSB-EP012376HO CSB-BP012376HO CSB-MP012376HO CSB-EP012376HO-B	Recombinant Horse Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376CH CSB-EP012376CH CSB-BP012376CH CSB-MP012376CH CSB-EP012376CH-B	Recombinant Chicken Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Bos taurus (Bovine)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376BO CSB-BP012376BO CSB-MP012376BO CSB-EP012376BO-B	Recombinant Bovine Kit ligand (KITLG), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP012376PI CSB-EP012376PI CSB-BP012376PI CSB-MP012376PI CSB-EP012376PI-B	Recombinant Pig Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-EP012376HU	Recombinant Human Kit ligand (KITLG), partial	E.coli
CSB-AP002061HU	Recombinant Human Kit ligand protein (KITLG), partial (Active)	E.Coli
CSB-CF012376HU(A4)	Recombinant Human Kit ligand (KITLG)	in vitro E.coli expression system
CSB-AP003741HU	Recombinant Human Kit ligand (KITLG), partial (Active)	E.coli
CSB-AP003881HU	Recombinant Human Kit ligand (KITLG), partial (Active)	Mammalian cell
CSB-MP002061HU	Recombinant Human Kit ligand (KITLG), partial	Mammalian cell