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KIT

KIT是一種受體酪氨酸激酶,全稱為"Kinase Insert Domain Receptor"(激酶插入域受體)。它在多種細(xì)胞類型中表達(dá),包括干細(xì)胞和造血細(xì)胞。KIT的作用機(jī)制主要通過與配體干細(xì)胞因子(stem cell factor, SCF)結(jié)合,激活下游信號(hào)通路,從而促進(jìn)細(xì)胞增殖、分化和存活。KIT對(duì)維持組織穩(wěn)態(tài)、傷口愈合及免疫反應(yīng)等過程具有重要意義。異常的KIT表達(dá)或功能失調(diào)與某些類型的癌癥,如胃腸道間質(zhì)瘤(GIST)和某些白血病有關(guān)。

熱銷產(chǎn)品

Recombinant Human Mast/stem cell growth factor receptor Kit (KIT), partial (CSB-MP012375HU)

驗(yàn)證數(shù)據(jù)

CSB-MP012375HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

KIT Antibody (CSB-PA07109A0Rb)

驗(yàn)證數(shù)據(jù)

CSB-PA07109A0Rb

Immunofluorescent analysis of MCF-7 cells using CSB-PA07109A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

KIT Antibodies

KIT for Homo sapiens (Human)

KIT Proteins

KIT Proteins for Homo sapiens (Human)

KIT Proteins for Bos taurus (Bovine)

KIT Proteins for Mus musculus (Mouse)

KIT Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

KIT Proteins for Gallus gallus (Chicken)

KIT Proteins for Felis catus (Cat) (Felis silvestris catus)

KIT Proteins for Capra hircus (Goat)

KIT Proteins for Sus scrofa (Pig)

KIT Proteins for Callithrix jacchus (White-tufted-ear marmoset)

KIT Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

KIT Proteins for Xenopus laevis (African clawed frog)

KIT ELISA Kit

KIT ELISA Kit for Homo sapiens (Human)