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IL7R

IL7R,即白細胞介素7受體,別名CD127。它是一種由IL7R基因編碼的蛋白質(zhì),屬于I型細胞因子受體家族,在多種免疫細胞表面表達,包括T細胞、B細胞和自然殺傷(NK)細胞。IL7R的作用機制涉及與其配體IL-7結(jié)合,激活JAK/STAT信號通路,促進免疫細胞的增殖、存活和分化。IL7R參與了免疫系統(tǒng)的發(fā)育和維持,特別是對T細胞亞群的調(diào)節(jié)作用。IL7R的表達水平在某些疾病中發(fā)生變化,如免疫缺陷病、癌癥和慢性感染,是免疫學研究和相關(guān)疾病治療中的一個潛在靶點。

熱銷產(chǎn)品

Recombinant Human Interleukin-7 receptor subunit alpha (IL7R), partial (CSB-EP011670HU1)

驗證數(shù)據(jù)

CSB-EP011670HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL7R Antibody (CSB-PA011670ESR1HU)

驗證數(shù)據(jù)

CSB-PA011670ESR1HU

Western blot
All lanes: IL7R antibody at 4µg/ml
Lane 1: K562 whole cell lysate
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 52, 35, 30, 29 kDa
Observed band size: 52 kDa  

CSB-PA011670ESR1HU

Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA011670ESR1HU at dilution of 1:100

CSB-PA011670ESR1HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA011670ESR1HU at dilution of 1:100

IL7R Antibodies

IL7R for Homo sapiens (Human)

IL7R Proteins

IL7R Proteins for Homo sapiens (Human)

IL7R Proteins for Mus musculus (Mouse)

IL7R Proteins for Equus caballus (Horse)

IL7R Proteins for Callithrix jacchus (White-tufted-ear marmoset)

IL7R Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

IL7R ELISA Kit

IL7R ELISA Kit for Homo sapiens (Human)

IL7R ELISA Kit for Mus musculus (Mouse)