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CLDN3

CLDN3(Claudin-3)是一種細胞間緊密連接的蛋白質(zhì),參與細胞的黏附和信號傳遞。它主要在上皮組織中表達,并參與調(diào)節(jié)細胞的極性、滲透性和細胞間通訊等功能。此外,CLDN3在許多癌癥中的表達升高,包括卵巢癌、乳腺癌、胃癌、前列腺癌等。許多研究表明,CLDN3可以作為腫瘤診斷和治療的潛在靶點。一些針對CLDN3的治療策略,例如抗CLDN3單克隆抗體、siRNA和小分子化合物,已被開發(fā),并在臨床試驗中得到驗證。因此,CLDN3的研究和開發(fā)具有重要的臨床意義,對于癌癥治療和預防具有重要的潛在價值。

更多相關閱讀:CLDN3,極為關鍵的緊密連接蛋白,Claudins家族再添藥物靶點!

熱銷產(chǎn)品

Recombinant Human Claudin-3(CLDN3)-VLPs (Active)(CSB-MP005505HU)

驗證數(shù)據(jù)

High Purity Validated by SDS-PAGE

The high specifity was validated by western blot. (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Immobilized Human CLDN3 at 10μg/mL can bind Anti-CLDN3 recombinant antibody (CSB-RA005505MA1HU), the EC50?is 23.62-34.37 ng/mL.VLPs (CSB-MP3838) is negative control.

CLDN3 Antibodies

CLDN3 for Homo sapiens (Human)

CLDN3 Proteins

CLDN3 Proteins for Homo sapiens (Human)

CLDN3 Proteins for Rattus norvegicus (Rat)

CLDN3 Proteins for Bos taurus (Bovine)

CLDN3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CLDN3 Proteins for Mus musculus (Mouse)

CLDN3 ELISA Kit

CLDN3 ELISA Kit for Homo sapiens (Human)