CDH17
CDH17指的是膽固醇黏附素家族成員17(Cadherin-17),也被稱為肝臟細(xì)胞間粘附分子(Liver-Cell Adhesion Molecule,L-CAM)。它是一種單個(gè)跨膜的細(xì)胞粘附分子,屬于鈣依賴性細(xì)胞粘附分子家族中的一員。CDH17主要在肝、膽管、胰腺、消化道和泌尿道等組織中表達(dá)。 CDH17的主要功能是調(diào)節(jié)細(xì)胞黏附、遷移和生長(zhǎng)等過程,參與了多種生理和病理過程。例如,在肝膽系統(tǒng)中,CDH17發(fā)揮了肝細(xì)胞和膽管上皮細(xì)胞之間的黏附作用,同時(shí)還參與了膽汁酸的轉(zhuǎn)運(yùn)和分泌。在胰腺癌中,CDH17的高表達(dá)與腫瘤的浸潤(rùn)和轉(zhuǎn)移有關(guān)。 因此,CDH17已成為潛在的治療靶點(diǎn),CUSABIO有多種CDH17單克隆抗體供您選擇。
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熱銷產(chǎn)品
● Recombinant Human Cadherin-17(CDH17),partial (Active) CSB-MP613267HU
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 at 2μg/mL can bind Anti-CDH17 recombinant antibody (CSB-RA613267MA1HU), the EC50 is 3.095 to 4.451 ng/mL.
● CDH17 Recombinant Monoclonal Antibody CSB-RA613267MA1HU
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human CDH17 with Anti-CDH17 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CDH17 (CSB-MP613267HU) at 2 μg/mL can bind Anti-CDH17 recombinant antibody, the EC50 is 3.095-4.451 ng/mL.
Untransfected HEK293T cells (green line) and transfected Human CDH17 HEK293T stable cells (red line) were stained with anti-CDH17 antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
CDH17 Antibodies
CDH17 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA613267ESR1HU | CDH17 Antibody | Human | ELISA, IHC |
CSB-PA212083 | CDH17 Antibody | Human | ELISA,WB,IF |
CSB-PA006407 | CDH17 Antibody | Human | WB, IHC, IF, ELISA |
CSB-PA017530LA01HU | PCDH17 Antibody | Human | ELISA, IF |
CSB-PA017530LD01HU | PCDH17 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA017530LC01HU | PCDH17 Antibody, FITC conjugated | Human | |
CSB-PA017530LB01HU | PCDH17 Antibody, HRP conjugated | Human | ELISA |
CDH17 Proteins
CDH17 Proteins for Rattus norvegicus (Rat)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP005042RA CSB-EP005042RA CSB-BP005042RA CSB-MP005042RA CSB-EP005042RA-B |
Recombinant Rat Cadherin-17 (Cdh17), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CDH17 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP017530HU CSB-EP017530HU CSB-BP017530HU CSB-MP017530HU CSB-EP017530HU-B |
Recombinant Human Protocadherin-17 (PCDH17), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP613267HU CSB-EP613267HU CSB-BP613267HU CSB-EP613267HU-B |
Recombinant Human Cadherin-17 (CDH17), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP613267HU | Recombinant Human Cadherin-17 (CDH17), partial (Active) | Mammalian cell |
CDH17 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-BP882608MO CSB-MP882608MO CSB-EP882608MO-B |
Recombinant Mouse Cadherin-17 (Cdh17), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP882608MO | Recombinant Mouse Cadherin-17 (Cdh17), partial | E.coli |
CSB-YP882608MO | Recombinant Mouse Cadherin-17 (Cdh17), partial | Yeast |
CSB-MP882608MO1 | Recombinant Mouse Cadherin-17 (Cdh17), partial | Mammalian cell |