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CD93

CD93最初被發(fā)現(xiàn)是與補(bǔ)體系統(tǒng)的C1q蛋白結(jié)合的一種膜受體,因此被命名為C1qRp。在許多不同的細(xì)胞類型中都有表達(dá),包括內(nèi)皮細(xì)胞、淋巴細(xì)胞、巨噬細(xì)胞和肝細(xì)胞等。在免疫反應(yīng)中,CD93可以作為一種識(shí)別并結(jié)合自身抗原的受體,在自身免疫性疾病和腫瘤的免疫治療中具有重要的作用。此外,CD93還參與了血管生成、細(xì)胞黏附和凋亡等生物學(xué)過程。近年來的研究表明,CD93也可能與神經(jīng)發(fā)育和神經(jīng)退行性疾病有關(guān)。一些研究表明,在神經(jīng)元的成熟和突觸形成過程中,CD93可以調(diào)節(jié)神經(jīng)細(xì)胞外基質(zhì)的合成和降解,從而對(duì)神經(jīng)元發(fā)育產(chǎn)生影響。在許多不同的生物學(xué)過程中都發(fā)揮著重要的作用。

更多CD93相關(guān)閱讀:抗腫瘤治療界后起之秀--CD93

熱銷產(chǎn)品

Recombinant Human Complement component C1q receptor(CD93),partial (Active) CSB-MP865099HU

驗(yàn)證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD93 at 2 μg/ml can bind Anti-CD93 recombinant antibody (CSB-RA865099MA1HU), the EC50 is 0.6639-1.173 ng/mL.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD93 at 2 μg/ml can bind Human IGFBP7 (CSB-MP620956HU), the EC50 is 20.34-26.92 ng/mL.

Recombinant Macaca fascicularis CD93 molecule(CD93),partial (Active) CSB-MP4279MOV

驗(yàn)證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CD93 at 2 μg/ml can bind Anti-CD93 recombinant antibody (CSB-RA865099MA1HU), the EC50 is 0.1669-0.3513 ng/mL.

Recombinant Mouse Complement component C1q receptor(Cd93),partial (Active) CSB-MP004970MO

驗(yàn)證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CD93 at 2 μg/mL can bind Mouse IGFBP7 (CSB-MP713980MO), the EC50 is 373.4-836.8 ng/mL.

CHOK1/Human CD93 Stable Cell Line CSB-SC865099HU

驗(yàn)證數(shù)據(jù)

FC
CSB-SC865099HU-FACS

Untransfected CHO-K1 cells (green line) and transfected Human CD93 CHOK1 Stable cells (red line) were stained with anti-CD93 antibody(CSB-RA865099MA1HU) (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

CD93 Antibodies

CD93 for Homo sapiens (Human)

CD93 Proteins

CD93 Proteins for Mus musculus (Mouse)

CD93 Proteins for Rattus norvegicus (Rat)

CD93 Proteins for Homo sapiens (Human)