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CD58

CD58,即細(xì)胞表面分化抗原58,別名LFA-3、WLA等。它是一種由CD58基因編碼的糖蛋白,主要表達(dá)在多種白細(xì)胞表面,包括T細(xì)胞、B細(xì)胞、自然殺傷(NK)細(xì)胞等。CD58的作用機(jī)制涉及與T細(xì)胞表面的CD2受體結(jié)合,參與免疫細(xì)胞間的相互作用,調(diào)節(jié)免疫應(yīng)答。CD58與CD2的相互作用對(duì)于T細(xì)胞的激活至關(guān)重要,影響細(xì)胞毒性T細(xì)胞的殺傷活性和細(xì)胞因子的產(chǎn)生。此外,CD58還參與了免疫逃逸機(jī)制,某些病原體如單純皰疹病毒(HSV)通過(guò)表達(dá)與CD58相似的蛋白來(lái)逃避宿主的免疫監(jiān)視,是免疫學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。

熱銷(xiāo)產(chǎn)品

CD58 Recombinant Monoclonal Antibody (CSB-RA166177A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA166177A0HU

Western Blot
Positive WB detected in: Raji whole cell lysate, K562 whole cell lysate, Hela whole cell lysate
All lanes: CD58 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29, 27, 26 kDa
Observed band size: 55-70 kDa

CD58 Antibodies

CD58 for Homo sapiens (Human)

CD58 Proteins

CD58 Proteins for Homo sapiens (Human)