CD47
CD47(也稱為Integrin-Associated Protein或IAP)是一種跨膜蛋白,它由五個外胞漿結(jié)構(gòu)域和一個短胞漿尾部組成。它的胞外結(jié)構(gòu)域與其他蛋白質(zhì)相互作用,而其胞內(nèi)尾部參與細胞內(nèi)信號傳導(dǎo)。。它在細胞表面廣泛分布,并在多種生物學(xué)過程中發(fā)揮著重要的作用。 CD47具有多種生物學(xué)功能,包括:自我識別,調(diào)控免疫反應(yīng),血細胞識別,腫瘤逃避免疫等。 對CD47的研究正在為免疫系統(tǒng)的調(diào)控和癌癥治療領(lǐng)域提供新的見解和治療策略。
更多相關(guān)閱讀:CD47:下一個腫瘤免疫研發(fā)熱點
熱銷產(chǎn)品
● Recombinant Human Leukocyte surface antigen CD47(CD47),partial (Active) CSB-MP004940HU
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized SIRPA (CSB-MP021334HU) at 2 μg/ml can bind human CD47, the EC50 of human CD47 protein is 65.91-82.42 ng/ml.
Human SIRPA protein His/Myc tag (CSB-MP021334HU) captured on COOH chip can bind Human CD47 protein Fc tag (CSB-MP004940HU) with an affinity constant of 19.1 nM as detected by LSPR Assay.
● CD47 Recombinant Monoclonal Antibody CSB-RA802124A0HU
驗證數(shù)據(jù)
Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate.All lanes: CD47 antibody at 1:2000,Secondary,Goat polyclonal to rabbit IgG at 1/50000 dilution,Predicted band size: 36, 32, 34 kDa,Observed band size: 55 kDa
IHC image of CSB-RA802124A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Immunofluorescence staining of MCF7 Cells with CSB-RA802124A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
CD47 Antibodies
CD47 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA004940GA01HU | CD47 Antibody | Human | ELISA,WB |
CSB-PA005993 | CD47 Antibody | Human | WB, ELISA |
CSB-PA445679 | CD47 Antibody | Human | ELISA,WB,IHC |
CSB-PA911004 | CD47 Antibody | Human | ELISA,IHC |
CSB-PA004940LA01HU | CD47 Antibody | Human | ELISA, IHC, IF |
CSB-PA004940LB01HU | CD47 Antibody, HRP conjugated | Human | ELISA |
CSB-PA004940LC01HU | CD47 Antibody, FITC conjugated | Human | |
CSB-PA004940LD01HU | CD47 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA802124A0HU | CD47 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF |
CD47 Proteins
CD47 Proteins for Rattus norvegicus (Rat)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP004940RA1 CSB-EP004940RA1 CSB-BP004940RA1 CSB-MP004940RA1 CSB-EP004940RA1-B |
Recombinant Rat Leukocyte surface antigen CD47 (Cd47), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004940RA | Recombinant Rat Leukocyte surface antigen CD47 (Cd47) | in vitro E.coli expression system |
CD47 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP713985MO1 CSB-EP713985MO1 CSB-BP713985MO1 CSB-MP713985MO1 CSB-EP713985MO1-B |
Recombinant Mouse Leukocyte surface antigen CD47 (Cd47), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF713985MO | Recombinant Mouse Leukocyte surface antigen CD47 (Cd47) | in vitro E.coli expression system |
CSB-AP005351MO | Recombinant Mouse Leukocyte surface antigen CD47 (Cd47), partial (Active) | Mammalian cell |
CD47 Proteins for Pongo abelii (Sumatran orangutan)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP729089PYX1 CSB-EP729089PYX1 CSB-BP729089PYX1 CSB-MP729089PYX1 CSB-EP729089PYX1-B |
Recombinant Pongo abelii Leukocyte surface antigen CD47 (CD47), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF729089PYX | Recombinant Pongo abelii Leukocyte surface antigen CD47 (CD47) | in vitro E.coli expression system |
CD47 Proteins for Sus scrofa (Pig)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP872379PI1 CSB-EP872379PI1 CSB-BP872379PI1 CSB-MP872379PI1 CSB-EP872379PI1-B |
Recombinant Pig Leukocyte surface antigen CD47 (CD47), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF872379PI | Recombinant Pig Leukocyte surface antigen CD47 (CD47) | in vitro E.coli expression system |
CD47 Proteins for Bos taurus (Bovine)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP885628BO1 CSB-EP885628BO1 CSB-BP885628BO1 CSB-MP885628BO1 CSB-EP885628BO1-B |
Recombinant Bovine Leukocyte surface antigen CD47 (CD47), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF885628BO | Recombinant Bovine Leukocyte surface antigen CD47 (CD47) | in vitro E.coli expression system |
CD47 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-AP005201HU | Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) | Mammalian cell |
CSB-AP005211HU | Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) | Mammalian cell |
CSB-MP004940HU | Recombinant Human Leukocyte surface antigen CD47 (CD47), partial (Active) | Mammalian cell |
CSB-MP004940HUj8-B | Recombinant Human Leukocyte surface antigen CD47 (CD47), partial,Biotinylated | Mammalian cell |
CD47 ELISA Kit
CD47 ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL004940HU | Human Leukocyte surface antigen CD47(CD47) ELISA kit | serum, plasma, urine, tissue homogenates | 0.78 pg/mL |
CD47 ELISA Kit for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL004940MO | Mouse Leukocyte surface antigen CD47(CD47) ELISA kit | serum, plasma,tissue homogenates | 3.9 pg/mL |