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CD2

CD2,即T細(xì)胞分化抗原2,別名Tp44、LFA-2、OKT11、T2等。它是一種由CD2基因編碼的細(xì)胞表面糖蛋白,屬于免疫球蛋白超家族成員,主要表達(dá)在所有成熟T細(xì)胞和一些自然殺傷(NK)細(xì)胞表面。CD2的作用機(jī)制涉及與細(xì)胞外配體如CD58結(jié)合,參與T細(xì)胞的激活、增殖和免疫突觸的形成,調(diào)節(jié)T細(xì)胞與其他免疫細(xì)胞的相互作用。CD2的功能異常與某些自身免疫性疾病和免疫缺陷有關(guān),例如,CD2基因的突變可能導(dǎo)致某些類型的免疫缺陷。因此,CD2是免疫學(xué)研究和相關(guān)疾病治療中的一個潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human T-cell surface antigen CD2 (CD2), partial (CSB-EP004894HU)

驗證數(shù)據(jù)

CSB-EP004894HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD2 Antibody (CSB-PA004894LA01HU)

驗證數(shù)據(jù)

CSB-PA004894LA01HU

Immunofluorescence staining of Hela cells with CSB-PA004894LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA004894LA01HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004894LA01HU at dilution of 1:100

CSB-PA004894LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004894LA01HU at dilution of 1:100

CD2 Antibodies

CD2 for Homo sapiens (Human)

CD2 for H, M, R

CD2 Proteins

CD2 Proteins for Equus caballus (Horse)

CD2 Proteins for Rattus norvegicus (Rat)

CD2 Proteins for Homo sapiens (Human)

CD2 Proteins for Mus musculus (Mouse)

CD2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)