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CADM1

CADM1(Cell Adhesion Molecule 1)也被稱為SynCAM1(Synaptic Cell Adhesion Molecule 1);參與多種生物學(xué)過程和疾病發(fā)生發(fā)展。 ADM1的胞外結(jié)構(gòu)域包括一個N-末端信號序列、三個Ig-like結(jié)構(gòu)域和一個C-末端結(jié)構(gòu)域,其中第一個Ig-like結(jié)構(gòu)域參與了細胞間的黏附和信號轉(zhuǎn)導(dǎo)。CADM1的細胞內(nèi)結(jié)構(gòu)域包括一個短的胞內(nèi)區(qū)域和一個長的胞內(nèi)區(qū)域,前者含有一個肽鍵酶切位點和幾個磷酸化位點,后者則包含多個蛋白質(zhì)相互作用位點和信號調(diào)節(jié)結(jié)構(gòu)域 它在神經(jīng)元、免疫細胞、腫瘤等細胞中表達,并通過其胞外結(jié)構(gòu)域和細胞內(nèi)信號通路影響細胞間的黏附、遷移、增殖和凋亡等生物學(xué)行為。

更多相關(guān)閱讀:CADM1/TSLC1:免疫球蛋白超家族黏附分子,一種新的TSG腫瘤抑制基因!

熱銷產(chǎn)品

Recombinant Mouse Cell adhesion molecule 1(Cadm1),partial (Active) CSB-MP004425MO

驗證數(shù)據(jù)

High Purity Validated by SDS-PAGE
CSB-MP004425MO SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA
CSB-MP004425MO AC

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CADM1 at 2μg/mL can bind Mouse CRTAM (CSB-MP614820MO), the EC50?is 52.61-92.92 ng/mL.?

CADM1 Antibodies

CADM1 for Homo sapiens (Human)

CADM1 Proteins

CADM1 Proteins for Mus musculus (Mouse)

CADM1 Proteins for Homo sapiens (Human)