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BDNF

BDNF,即腦源性神經(jīng)營養(yǎng)因子,別名Neurotrophin、Abrineurin等。它來源于大腦內(nèi)的神經(jīng)元和膠質(zhì)細(xì)胞,是一種由這些細(xì)胞分泌的蛋白質(zhì)。BDNF的作用機(jī)制主要通過與酪氨酸激酶B(TrkB)受體結(jié)合,激活下游信號(hào)通路,如Ras-MAPK和PI3K-Akt,進(jìn)而促進(jìn)神經(jīng)元的存活、分化、生長和突觸可塑性。在生物學(xué)上,BDNF對維持中樞及周圍神經(jīng)系統(tǒng)的正常生理功能至關(guān)重要,同時(shí)也是治療神經(jīng)退行性疾病、抑郁癥、焦慮癥等精神疾病的重要靶點(diǎn)。此外,BDNF還參與記憶的形成和鞏固,對學(xué)習(xí)和認(rèn)知能力有重要影響。

熱銷產(chǎn)品

Recombinant Human Brain-derived neurotrophic factor (BDNF), partial (CSB-EP002655HU(A4))

驗(yàn)證數(shù)據(jù)

CSB-EP002655HU(A4)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

BDNF Recombinant Monoclonal Antibody (CSB-RA989910A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA989910A0HU

Western Blot
Positive WB detected in: U87 whole cell lysate, U251 whole cell lysate, Mouse Brain tissue lysate
All lanes: BDNF antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 28 kDa
Observed band size: 28 kDa

BDNF Antibodies

BDNF for Homo sapiens (Human)

BDNF for Rattus norvegicus (Rat)

BDNF Proteins

BDNF Proteins for Sus scrofa (Pig)

BDNF Proteins for Mus musculus (Mouse)

BDNF Proteins for Gallus gallus (Chicken)

BDNF Proteins for Homo sapiens (Human)

BDNF Proteins for Rattus norvegicus (Rat)

BDNF Proteins for Cavia porcellus (Guinea pig)

BDNF Proteins for Procyon lotor (Raccoon)

BDNF Proteins for Ursus malayanus (Malayan sun bear) (Helarctos malayanus)

BDNF Proteins for Ursus arctos (Brown bear) (Grizzly bear)

BDNF Proteins for Ailurus fulgens (Lesser panda) (Red panda)

BDNF Proteins for Xenopus laevis (African clawed frog)

BDNF Proteins for Raja clavata (Thornback ray)

BDNF Proteins for Macrovipera lebetina (Levantine viper) (Vipera lebetina)

BDNF Proteins for Ailuropoda melanoleuca (Giant panda)

BDNF Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

BDNF Proteins for Cyprinus carpio (Common carp)

BDNF Proteins for Bos taurus (Bovine)

BDNF Proteins for Cyclophiops major (Giant green snake)

BDNF Proteins for Felis catus (Cat) (Felis silvestris catus)

BDNF Proteins for Equus caballus (Horse)

BDNF Proteins for Aspidites melanocephalus (Black-headed python)

BDNF Proteins for Charina trivirgata (Rosy boa) (Lichanura trivirgata)

BDNF Proteins for Epicrates striatus (Hispaniolan common boa) (Bahama boa)

BDNF Proteins for Xenopeltis unicolor (Sunbeam snake)

BDNF Proteins for Eryx jayakari (Arabian sand boa)

BDNF Proteins for Eryx johnii (Indian sand boa) (Boa johnii)

BDNF Proteins for Eryx colubrinus colubrinus

BDNF Proteins for Loxocemus bicolor (Mexican python)

BDNF Proteins for Anilius scytale (Red pipe snake)

BDNF Proteins for Candoia carinata (Papuan tree boa)

BDNF Proteins for Calabaria reinhardtii (Calabar boa) (Calabar ground python)

BDNF Proteins for Exiliboa placata (Oaxacan dwarf boa)

BDNF Proteins for Acrochordus javanicus (Javan wart snake)

BDNF Proteins for Eunectes notaeus (Yellow anaconda)

BDNF Proteins for Charina bottae (Northern rubber boa)

BDNF Proteins for Sanzinia madagascariensis (Madagascar tree boa) (Boa manditra)

BDNF Proteins for Ramphotyphlops sp. (strain YPM 13663) (Blind snake)

BDNF Proteins for Morelia spilota (Carpet python)

BDNF Proteins for Corallus caninus (Emerald tree boa)

BDNF Proteins for Tropidophis haetianus (Haitian dwarf boa)

BDNF Proteins for Epicrates cenchria (Rainbow boa)

BDNF Proteins for Cylindrophis ruffus (Red-tailed pipe snake)

BDNF Proteins for Boa constrictor (Boa)

BDNF Proteins for Eryx conicus (Rough-scaled sand boa) (Gongylophis conicus)

BDNF Proteins for Acrantophis dumerili (Dumeril's ground boa) (Boa dumerili)

BDNF Proteins for Ursus thibetanus (Asiatic black bear) (Selenarctos thibetanus)

BDNF Proteins for Lipotes vexillifer (Yangtze river dolphin)

BDNF Proteins for Spermophilus citellus (European suslik) (Citellus citellus)

BDNF Proteins for Pan troglodytes (Chimpanzee)

BDNF ELISA Kit

BDNF ELISA Kit for Homo sapiens (Human)

BDNF ELISA Kit for Monkey

BDNF ELISA Kit for Mus musculus (Mouse)

BDNF ELISA Kit for Sus scrofa (Pig)

BDNF ELISA Kit for Rattus norvegicus (Rat)