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ATG5

Autophagy protein 5 is a protein in humans that is encoded by ATG5 gene. Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.

ATG5 Antibodies

ATG5 for Homo sapiens (Human)

ATG5 Proteins

ATG5 Proteins for Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)

ATG5 Proteins for Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans)

ATG5 Proteins for Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)

ATG5 Proteins for Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)

ATG5 Proteins for Oryza sativa subsp. indica (Rice)

ATG5 Proteins for Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)

ATG5 Proteins for Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)

ATG5 Proteins for Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)

ATG5 Proteins for Saccharomyces cerevisiae (strain YJM789) (Baker's yeast)

ATG5 Proteins for Ajellomyces capsulata (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)

ATG5 Proteins for Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)

ATG5 Proteins for Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)

ATG5 Proteins for Pichia angusta (Yeast) (Hansenula polymorpha)

ATG5 Proteins for Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) (Penicillium notatum)

ATG5 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

ATG5 Proteins for Aspergillus terreus (strain NIH 2624 / FGSC A1156)

ATG5 Proteins for Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)

ATG5 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

ATG5 Proteins for Coccidioides immitis (strain RS) (Valley fever fungus)

ATG5 Proteins for Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)

ATG5 Proteins for Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)

ATG5 Proteins for Sus scrofa (Pig)

ATG5 Proteins for Bos taurus (Bovine)

ATG5 Proteins for Rattus norvegicus (Rat)

ATG5 Proteins for Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

ATG5 Proteins for Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)

ATG5 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

ATG5 Proteins for Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)

ATG5 Proteins for Dictyostelium discoideum (Slime mold)

ATG5 Proteins for Pongo abelii (Sumatran orangutan)

ATG5 Proteins for Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)

ATG5 Proteins for Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)

ATG5 Proteins for Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)

ATG5 Proteins for Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)

ATG5 Proteins for Oryza sativa subsp. japonica (Rice)

ATG5 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)

ATG5 Proteins for Mus musculus (Mouse)

ATG5 Proteins for Homo sapiens (Human)

ATG5 Proteins for Arabidopsis thaliana (Mouse-ear cress)

ATG5 Proteins for Drosophila melanogaster (Fruit fly)