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ARID1A

ARID1A,即AT豐富結(jié)合域1A基因,它是一種SWI/SNF染色質(zhì)重塑復(fù)合物家族中的重要成員,主要來(lái)源于染色體1p36.11上的位置。ARID1A的作用機(jī)制包括與DNA非特異性結(jié)合,調(diào)節(jié)細(xì)胞周期、細(xì)胞增殖、DNA損傷修復(fù)等細(xì)胞生命活動(dòng)。ARID1A作為腫瘤抑制因子,在多種腫瘤中發(fā)生突變或缺失,對(duì)腫瘤的發(fā)生發(fā)展具有重要影響,其功能喪失可能導(dǎo)致腫瘤細(xì)胞的增殖和侵襲性增強(qiáng)。

熱銷(xiāo)產(chǎn)品

Recombinant Human AT-rich interactive domain-containing protein 1A (ARID1A), partial (CSB-EP002058HU1)

驗(yàn)證數(shù)據(jù)

CSB-EP002058HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-EP002058HU1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002058HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ARID1A.

CSB-EP002058HU1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP002058HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ARID1A.

ARID1A Antibody (CSB-PA040400)

驗(yàn)證數(shù)據(jù)

CSB-PA040400

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA040400(ARID1A Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA040400

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA040400(ARID1A Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)

ARID1A Antibodies

ARID1A for Homo sapiens (Human)

ARID1A Proteins

ARID1A Proteins for Mus musculus (Mouse)

ARID1A Proteins for Homo sapiens (Human)