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AHR

AHR,即芳烴受體,別名Aryl Hydrocarbon Receptor、ARY1等。它是一種由AHR基因編碼的核受體,廣泛分布于各種組織中。AHR的作用機(jī)制涉及與芳香烴類(lèi)化合物如二噁英、多環(huán)芳烴等結(jié)合,激活后從細(xì)胞質(zhì)轉(zhuǎn)移到細(xì)胞核,與芳香烴受體核轉(zhuǎn)運(yùn)蛋白(ARNT)形成異源二聚體,結(jié)合到DNA上的芳烴受體元件(DRE),調(diào)控下游基因的表達(dá)。AHR參與調(diào)節(jié)細(xì)胞周期、細(xì)胞增殖、分化、代謝和免疫應(yīng)答等過(guò)程。AHR的異常激活與肺癌、皮膚癌等癌癥的發(fā)生發(fā)展有關(guān),是環(huán)境毒理學(xué)和疾病治療研究中的一個(gè)重要靶點(diǎn)。

熱銷(xiāo)產(chǎn)品

Recombinant Human Aryl hydrocarbon receptor (AHR), partial (CSB-EP001481HU3)

驗(yàn)證數(shù)據(jù)

CSB-EP001481HU3

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

AHR Antibody (CSB-PA001481LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA001481LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA001481LA01HU at dilution of 1:100

CSB-PA001481LA01HU

Immunofluorescent analysis of MCF-7 cells using CSB-PA001481LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human aryl hydrocarbon receptor,AhR ELISA Kit (CSB-E09355h)

驗(yàn)證數(shù)據(jù)

CSB-E09355h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E09355h

規(guī)格:96T/48T

靈敏度:3.9 pg/mL

檢測(cè)范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

AHR Antibodies

AHR for Homo sapiens (Human)

AHR Proteins

AHR Proteins for Mus musculus (Mouse)

AHR Proteins for Homo sapiens (Human)

AHR Proteins for Oryctolagus cuniculus (Rabbit)

AHR Proteins for Rattus norvegicus (Rat)

AHR Proteins for Mus caroli (Ryukyu mouse) (Ricefield mouse)

AHR Proteins for Mus musculus molossinus (Japanese house mouse)

AHR Proteins for Mus spretus (Western Mediterranean mouse) (Algerian mouse)

AHR Proteins for Mus musculus castaneus (Southeastern Asian house mouse)

AHR Proteins for Delphinapterus leucas (Beluga whale)

AHR Proteins for Mus spicilegus (Steppe mouse)

AHR ELISA Kit

AHR ELISA Kit for Homo sapiens (Human)