5HT1A
5HT1A，即5-羥色胺1A受體，別名 HTR1A、ADRBRL1、5-HT1A。它是一種G蛋白偶聯(lián)受體，由人體細(xì)胞自身的基因編碼，主要在大腦、脊髓、胃腸道等部位表達(dá)。5HT1A受體的作用機(jī)制涉及與5-羥色胺（5-HT）結(jié)合，激活后通過(guò)G蛋白信號(hào)轉(zhuǎn)導(dǎo)，影響細(xì)胞內(nèi)的cAMP水平，進(jìn)而調(diào)控細(xì)胞功能。5HT1A受體在生物學(xué)上的意義非常廣泛，它參與調(diào)節(jié)情緒、睡眠、疼痛感知、認(rèn)知功能等多種生理過(guò)程，是抗抑郁藥、抗焦慮藥等藥物研發(fā)的重要靶點(diǎn)。異常的5HT1A受體功能與抑郁癥、焦慮癥、精神分裂癥等精神疾病有關(guān)，其激動(dòng)劑或拮抗劑在臨床上用于治療這些疾病。
熱銷產(chǎn)品
HTR1A Antibody (CSB-PA010881LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry analysis of human small intestine tissue using CSB-PA010881LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA010881LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
5HT1A Antibodies
5HT1A for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA004142 | HTR1A Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA830794 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA109594 | HTR1A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA010881LA01HU | HTR1A Antibody | Human | ELISA, IHC, IF |
| CSB-PA010881LC01HU | HTR1A Antibody, FITC conjugated | Human | |
| CSB-PA010881LD01HU | HTR1A Antibody, Biotin conjugated | Human | ELISA |
5HT1A Proteins
5HT1A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP010881HU1 CSB-EP010881HU1 CSB-BP010881HU1 CSB-MP010881HU1 CSB-EP010881HU1-B |
Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010881HU | Recombinant Human 5-hydroxytryptamine receptor 1A (HTR1A) | in vitro E.coli expression system |
