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SLC1A2

SLC1A2,即溶質載體家族1成員2,別名EAAT2、GLT-1等。它是一種由SLC1A2基因編碼的跨膜蛋白,主要在大腦神經(jīng)元和膠質細胞中表達。SLC1A2的作用機制涉及介導細胞外谷氨酸的轉運,將其帶入細胞內,對維持中樞神經(jīng)系統(tǒng)的谷氨酸穩(wěn)態(tài)至關重要。SLC1A2參與了神經(jīng)遞質谷氨酸的再攝取過程,對調節(jié)神經(jīng)興奮性和抑制性平衡具有重要作用。SLC1A2的功能異常與多種神經(jīng)系統(tǒng)疾病有關,如癲癇、神經(jīng)退行性疾病、腦損傷等。

熱銷產(chǎn)品

SLC1A2 Recombinant Monoclonal Antibody (CSB-RA051685A0HU)

驗證數(shù)據(jù)

CSB-RA051685A0HU

Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: EAAT2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62 kDa
Observed band size: 62 kDa

CSB-RA051685A0HU

Overlay Peak curve showing MCF-7 cells surface stained with CSB-RA051685A0HU (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

SLC1A2 Antibodies

SLC1A2 for Homo sapiens (Human)

SLC1A2 Proteins

SLC1A2 Proteins for Rattus norvegicus (Rat)

SLC1A2 Proteins for Homo sapiens (Human)

SLC1A2 Proteins for Mus musculus (Mouse)