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Recombinant Xenopus laevis Cadherin-1 (cdh1)

  • 中文名稱：
    Recombinant Xenopus laevis Cadherin-1(cdh1)
  • 貨號：
    CSB-CF005034XBE
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    cdh1
  • Uniprot No.：
  • 別名：
    cdh1; Cadherin-1; Epithelial cadherin; E-cadherin; Uvomorulin; xTCAD-1
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    149-872
  • 氨基酸序列
    DWVIPPIIVSENEKGPFPKRIVQIKSSYAKEVKVYYSITGQGADTPPEGVFAIGREDGWLNVTRPLDREAIDNYVLFSHAVSSNGANVEDPMEIIIKVQDQNDNDPVFTQSVFEGSVPEGSKPGTAVMTVSATDADDSVDMYNGVITYSILNQEPKEPTNKMFTIHSESGLISVLTTGLDREKNPVYTLTIQAADGEFGKDRTTTATALIVVMDTNDNPPVFDPTQYTAKVPENEVGYEVARLTVTDEDIEGTDAWNAVYKIIKGNEANYFSIQTDTGNIGLLKTVKGLDYELKKQYILSVIVTNKANFSVPLQTSTATVTVSVEDVNEAPIFLPPVKEVSVSEDLPSGQVVATYTAQDPDKEQNQKITYVIGNDPAGWVSVNKDNGIVTGNGNLDRESKFVLNNTYKVIILAADSGSPSATGTGTLVLNLLDVNDNGPFLEPQQESFCQKDPGFRVFTIIDRDLSPNTYPYKAELTGESNENWTAIVTGQSILELRPKKELEIGQYDVMITLLDSFGLSNVTKLHITICQCDGDKMQCEEKAAIAGGLGISAIVGILGGILALLLLLLLLLLFVRRKKVVKEPLLPPEDETRDNVFSYDEEGGGEEDQDFDLSQLHRGLDARPDVIRNDVAPVLAAPQYRPRPANPDEIGNFIDENLNAADNDPTAPPYDSLLVFDYEGSGSEAASLSSLNSPNSDLDQDYSALNDWGPRFTKLADMYGGDED
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-cadherin is a ligand for integrin alpha-E/beta-7.
  • 基因功能參考文獻(xiàn)：
    1. JNK deficient embryos also have increased intercellular adhesion and defects in e-cadherin localization. Conversely, embryos with overactive JNK have epidermal fragility, increased E-cadherin internalization, and increased membrane localized clathrin. PMID: 28032936
  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Non-neural epithelial tissues.
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:100337618

    UniGene: Xl.7483