Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Transcription initiation protein SPT3 homolog (SUPT3H)

Recombinant Human Transcription initiation protein SPT3 homolog (SUPT3H)

  • 中文名稱：
    人SUPT3H重組蛋白
  • 貨號：
    CSB-YP022956HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SUPT3H重組蛋白
  • 貨號：
    CSB-EP022956HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SUPT3H重組蛋白
  • 貨號：
    CSB-BP022956HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SUPT3H重組蛋白
  • 貨號：
    CSB-MP022956HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUPT3H
  • Uniprot No.：
  • 別名：
    SUPT3H; SPT3; Transcription initiation protein SPT3 homolog; SPT3-like protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-399
  • 氨基酸序列
    MYSPRGSQGR GTAEATANSP SPPIAPSHSR VTFSLSTLHT LSPPPRPFPS VSRAAAQKPH HLHPHILLAG SAAVPPRVLK AEMNNTAASP MSTATSSSGR STGKSISFAT ELQSMMYSLG DARRPLHETA VLVEDVVHTQ LINLLQQAAE VSQLRGARVI TPEDLLFLMR KDKKKLRRLL KYMFIRDYKS KIVKGIDEDD LLEDKLSGSN NANKRQKIAQ DFLNSIDQTG ELLAMFEDDE IDEVKQERME RAERQTRIMD SAQYAEFCES RQLSFSKKAS KFRDWLDCSS MEIKPNVVAM EILAYLAYET VAQLVDLALL VRQDMVTKAG DPFSHAISAT FIQYHNSAES TAACGVEAHS DAIQPCHIRE AIRRYSHRIG PLSPFTNAYR RNGMAFLAC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probable transcriptional activator.
  • 基因功能參考文獻：
    1. significance of the formation PVT1- SUPT3H chimeric gene remains unknown and the overexpression of MYC by ectopic promoter on chromosome 6 may be essential to tumor genesis. PMID: 25860292
    2. we identified rs41314453 as the main genetic determinant of ADAMTS13 activity, and we present preliminary findings for further associations at the ADAMTS13 and SUPT3H loci. PMID: 25934476
    3. identified a significant excess of genes with pivotal roles in bone homeostasis, such as PPPT3B and the height associated SUPT3H-RUNX2 PMID: 22407027
    4. suggest a novel STAF65gamma-dependent function of STAGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and RNA polymerase II that involves direct recruitment of core Mediator PMID: 17967894
    5. Found evidence of Mendelian Transmission Distortion in the region harboring SUPT3H in one HapMap population. PMID: 19259136

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    SPT3 family
  • 組織特異性：
    Expressed in all tissues tested including pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11466

    OMIM: 602947

    STRING: 9606.ENSP00000360515

    UniGene: Hs.368325