Recombinant Human Adenine phosphoribosyltransferase (APRT)
-
中文名稱:Recombinant Human Adenine phosphoribosyltransferase(APRT)
-
貨號:CSB-EP001954HU
-
規(guī)格:¥1344
-
圖片:
-
其他:
產(chǎn)品詳情
-
純度:Greater than 90% as determined by SDS-PAGE.
-
基因名:APRT
-
Uniprot No.:
-
別名:Adenine phosphoribosyltransferase; AMP; AMP diphosphorylase; AMP pyrophosphorylase; APRT; APT_HUMAN; DKFZp686D13177; MGC125856; MGC125857; MGC129961; Transphosphoribosidase
-
種屬:Homo sapiens (Human)
-
蛋白長度:Full Length
-
來源:E.coli
-
分子量:46.5kDa
-
表達區(qū)域:1-180aa
-
氨基酸序列MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. -
蛋白標簽:N-terminal GST-tagged
-
產(chǎn)品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液:Tris-based buffer,50% glycerol
-
儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保質(zhì)期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
-
注意事項:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
Datasheet & COA:Please contact us to get it.
相關產(chǎn)品
靶點詳情
-
功能:Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
-
基因功能參考文獻:
- A long TA repeat in the promoter region of IL28B was associated with spontaneous HCV clearance. PMID: 25735432
- A new mutation, p.Gln147X, in APRT gene, was found in a patient with adenine phosphoribosyltransferase deficiency. PMID: 24986359
- Case study of 2 year old Japanese boy with APRT deficiency. Genetic analysis showed compound heterozygote APRT*J and missense mutation L33P. APRT deficiency should be suspected in patients with radiolucent kidney stones and urinary 2,8-DHA crystals. PMID: 21635362
- kinetic, regulatory and thermostability properties of APRT from erythrocytes of HGPRT deficient patients PMID: 14674717
- determination of structure and examination of role of deficiency in DHA-urolithiasis PMID: 15196008
- two novel mutations, G133D and V84M, were found in the APRT gene in Japanese patients with APRT deficiency PMID: 15571218
- APRT assay in a sample of patient hemolysate showed no detectable activity of the enzyme (25.56+/-9.55 U/L red blood cells in control healthy subjects). PMID: 17126311
- Data indicates that the flexible loop structure adopts an open conformation before and after binding of both substrates adenine and phosphoribosyl pyrophosphate. PMID: 18399692
- The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP are reported. PMID: 19399589
顯示更多
收起更多
-
相關疾?。?/div>Adenine phosphoribosyltransferase deficiency (APRTD)亞細胞定位:Cytoplasm.蛋白家族:Purine/pyrimidine phosphoribosyltransferase family數(shù)據(jù)庫鏈接:
Most popular with customers
-
Recombinant Macaca mulatta Microtubule-associated protein tau (MAPT) (Active)
Express system: Mammalian cell
Species: Macaca mulatta (Rhesus macaque)
-
Recombinant Human Zymogen granule protein 16 homolog B (ZG16B) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Epithelial discoidin domain-containing receptor 1 (DDR1), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Early activation antigen CD69 (CD69), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Cell adhesion molecule 1 (CADM1), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Macaca fascicularis CUB domain containing protein 1 (CDCP1), partial (Active)
Express system: Mammalian cell
Species: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
-
Recombinant Human CD70 antigen (CD70), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-