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UGGT2 Antibody

  • 中文名稱(chēng)：
    UGGT2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA968491
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA968491(UGGT2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA968491(UGGT2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    UGGT2 antibody; UGCGL2 antibody; UGT2UDP-glucose:glycoprotein glucosyltransferase 2 antibody; UGT2 antibody; hUGT2 antibody; EC 2.4.1.- antibody; UDP--Glc:glycoprotein glucosyltransferase 2 antibody; UDP-glucose ceramide glucosyltransferase-like 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Full length fusion protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
  • 基因功能參考文獻(xiàn)：
    1. In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. PMID: 27496766
    2. The glucosyltransferase activity of UGGT2 has been lacking, leaving it unclear as to whether it has any function in the glycoprotein folding process. PMID: 24415556
    3. HUGT2 cannot activate the catalytic domain of UDP-glucose: glycoprotein glucosyltransferase I PMID: 12913004
  • 亞細(xì)胞定位：
    Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
  • 蛋白家族：
    Glycosyltransferase 8 family
  • 組織特異性：
    Higher levels in kidney, pancreas, heart, and skeletal muscle.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 15664

    OMIM: 605898

    KEGG: hsa:55757

    STRING: 9606.ENSP00000365938

    UniGene: Hs.193226