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TNFAIP2 Antibody

  • 中文名稱：
    TNFAIP2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA556193
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA556193(TNFAIP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TNFAIP2
  • 別名：
    B94 antibody; EXOC3L3 antibody; exocyst complex component 3-like 3 antibody; Primary response gene B94 protein antibody; TNAP2_HUMAN antibody; TNF alpha-induced protein 2 antibody; Tnfaip2 antibody; tumor necrosis factor alpha induced protein 2 antibody; Tumor necrosis factor alpha-induced protein 2 antibody; tumor necrosis factor, alpha-induced protein 2 antibody antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human TNFAIP2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:30-1:150
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role as a mediator of inflammation and angiogenesis.
  • 基因功能參考文獻(xiàn)：
    1. A polarized secretion assay suggested that the silencing of endothelial myeloid-secretory impairs T effector transendothelial migration by reducing the preferential secretion of endothelial-produced CCL2. PMID: 26701136
    2. Data indicate that TNFAIP2 overexpression may facilitate proliferation and metastasis via activation of the Wnt/beta-catenin signaling pathway in esophageal squamous cell carcinoma. PMID: 28393234
    3. Taken together, genome-wide chromatin analysis of Legionella pneumophila-infected macrophages demonstrated induction of TNFAIP2, a NF-kappaB-dependent factor relevant for bacterial replication. PMID: 27130431
    4. data suggest that TNFAIP2 is a novel inhibitor of NF-kappa-B that acts as an autoinhibitor of the TNFalpha response during septic shock. PMID: 26347487
    5. findings collectively suggest that TNFAIP2 is a direct KLF5 target gene, and both KLF5 and TNFAIP2 promote breast cancer cell proliferation, migration and invasion through Rac1 and Cdc42 PMID: 26189798
    6. A functional TNFAIP2 3'-UTR rs8126 genetic polymorphism contributes to risk of esophageal squamous cell carcinoma. PMID: 25383966
    7. the regulation of TNFAIP2 and its role in promoting NPC tumor progression PMID: 23975427
    8. The TNFAIP2 miRNA binding site rs8126 T>C single nucleotide polymorphism may be a marker for susceptibility to gastric cancer. PMID: 23724109
    9. A functional variant at the miR-184 binding site in TNFAIP2 is associated with squamous cell carcinoma of the head and neck. PMID: 21934093
    10. TNFAIP2 may serve as a useful new marker of dendritic and histiocytic sarcomas. PMID: 21921781
    11. TNFAIP2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
    12. TNFAIP2 is a cell migration-promoting protein and its expression predicts distant metastasis. Our data suggest that TNFAIP2 may serve as an independent prognostic indicator for nasopharyngeal carcinoma. PMID: 21057457

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  • 蛋白家族：
    SEC6 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11895

    OMIM: 603300

    KEGG: hsa:7127

    STRING: 9606.ENSP00000332326

    UniGene: Hs.525607