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TCF19 Antibody, FITC conjugated

  • 中文名稱：
    TCF19兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA023295LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TCF19 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TCF19
  • 別名：
    Transcription factor 19 (TCF-19) (Transcription factor SC1), TCF19, SC1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription factor 19 protein (12-250aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest TCF19 interacts with histone 3 lysine 4 trimethylation through its plant homeodomain finger; TCF19 expression appears to regulate gluconeogenesis in hepatocytes; TCF19 interacts with CHD4 causing NuRD complex recruitment to gene promoters of enzymes involved in gluconeogenesis. (TCF19 = transcription factor 19; CHD4 = chromodomain helicase DNA binding protein 4; NuRD = nucleosome-remodeling-deacetylase) PMID: 29042441
    2. Genome association studies identified TCF19 as a new risk-associated loci for chronic hepatitis B on the HLA region of chromosome 6. PMID: 23760081
    3. Data shows increased apoptosis and susceptibility to endoplasmic reticulum (ER) stress after Tcf19 knockdown. PMID: 23860123
    4. Knockdown of Tcf19 reduces proliferation and increases apoptosis. Tcf19 is found in pancreatic islets in mouse and human. PMID: 23860123
    5. A linkage disequilibrium analysis established TCF19, POU5F1, CCHCR1 and PSORS1C1 as potential causal genes for the type 1 diabetes. PMID: 21076979

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  • 亞細(xì)胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11629

    OMIM: 600912

    KEGG: hsa:6941

    STRING: 9606.ENSP00000365431

    UniGene: Hs.584807