Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Ms4a1 Antibody, FITC conjugated

Ms4a1 Antibody, FITC conjugated

  • 中文名稱：
    Ms4a1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA015007LC01MO
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Ms4a1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Ms4a1
  • 別名：
    Ms4a1 antibody; Cd20 antibody; Ly-44 antibody; Ms4a2 antibody; B-lymphocyte antigen CD20 antibody; B-cell differentiation antigen Ly-44 antibody; Lymphocyte antigen 44 antibody; Membrane-spanning 4-domains subfamily A member 1 antibody; CD antigen CD20 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse B-lymphocyte antigen CD20 protein (111-291AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
  • 基因功能參考文獻(xiàn)：
    1. Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment PMID: 28533311
    2. Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model PMID: 26888257
    3. Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy. PMID: 26261496
    4. this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity. PMID: 23966626
    5. CD20 is required for store-operated calcium entry in C2C12 myoblasts. PMID: 22982241
    6. immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells. PMID: 20189250
    7. type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling PMID: 20354182
    8. CD20 deficiency in humans results in impaired T cell-independent antibody responses. PMID: 20038800
    9. review of structure, function, tissue and cell distribution PMID: 12144126
    10. Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression. PMID: 15210744
    11. expression in bacterial cells; isolation and biophysical and structural studies PMID: 16285718
    12. In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice PMID: 18354225
    13. involvement of CD20 in calcium influx PMID: 18474602

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
  • 蛋白家族：
    MS4A family
  • 數(shù)據(jù)庫鏈接：