LAS1L Antibody
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中文名稱:LAS1L兔多克隆抗體
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貨號:CSB-PA897285LA01HU
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規(guī)格:¥440
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促銷:
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圖片:
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Western Blot
Positive WB detected in: 293 whole cell lysate
All lanes: LAS1L antibody at 3.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 84, 82, 77, 34 kDa
Observed band size: 84 kDa -
Immunofluorescence staining of HepG2 cells with CSB-PA897285LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) LAS1L Polyclonal antibody
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Uniprot No.:
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基因名:LAS1L
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別名:dJ475B7.2 antibody; FLJ12525 antibody; FLJ30133 antibody; FLJ45274 antibody; LAS1 like (S. cerevisiae) antibody; Las1 like antibody; LAS1L antibody; LAS1L_HUMAN antibody; Protein LAS1 homolog antibody; Ribosomal biogenesis protein LAS1L antibody; RP3 475B7.2 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Ribosomal biogenesis protein LAS1L protein (490-565AA)
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
本頁面中的產(chǎn)品,LAS1L Antibody (CSB-PA897285LA01HU),的標記方式是Non-conjugated。對于LAS1L Antibody,我們還提供其他標記。見下表:
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, WB, IF
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:5000 IF 1:200-1:500 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
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基因功能參考文獻:
- LAS1L interacts with PELP1, TEX10, and WDR18, the mammalian homologues of the budding yeast Rix1 complex, along with NOL9 and SENP3, to form a novel nucleolar complex that cofractionates with the 60S preribosomal subunit. PMID: 22190735
- Analysis of high-molecular-weight RNAs confirmed that Las1L is required for ITS2 processing,which separates the 5.8S and 25S/28S rRNAs, as 32S was found to accumulate and 12S to diminish upon Las1L depletion. PMID: 22083961
- Data demonstrate that Las1L is essential for cell proliferation and biogenesis of the 60S ribosomal subunit. PMID: 20647540
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相關(guān)疾?。?/div>Wilson-Turner X-linked mental retardation syndrome (WTS)亞細胞定位:Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm.蛋白家族:LAS1 family數(shù)據(jù)庫鏈接:
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