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L1 Antibody, Biotin conjugated

  • 中文名稱：
    L1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA08359D0Rb
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Human papillomavirus type 18 L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    L1
  • 別名：
    L1 antibody; Major capsid protein L1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human papillomavirus type 18
  • 免疫原：
    Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
  • 免疫原種屬：
    Human papillomavirus type 18
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
  • 基因功能參考文獻(xiàn)：
    1. L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA PMID: 16472835
  • 亞細(xì)胞定位：
    Virion. Host nucleus.
  • 蛋白家族：
    Papillomaviridae L1 protein family
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:1489090