GRIN3B Antibody
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) GRIN3B Polyclonal antibody
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Uniprot No.:
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基因名:
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別名:GluN3B antibody; Glutamate [NMDA] receptor subunit 3B antibody; Glutamate receptor ionotropic N methyl D aspartate 3B antibody; Glutamate receptor ionotropic NMDA 3B antibody; GRIN3B antibody; N-methyl-D-aspartate receptor subtype 3B antibody; NMD3B_HUMAN antibody; NMDA receptor subunit 3B antibody; NMDA type glutamate receptor subunit NR3B antibody; NMDAR3B antibody; NR3B antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Glutamate receptor ionotropic, NMDA 3B protein (180-410AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
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基因功能參考文獻(xiàn):
- GRIN3B missense mutation is an inherited risk factor for schizophrenia. PMID: 28132660
- Authors investigated the significance of a common human genetic variation of the NMDAR NR3B subunit PMID: 25768306
- Rs2240158 of GRIN3B was significantly associated with mismatch negativity in healthy subjects. PMID: 24814139
- our findings suggest that the over-expression of NR3B subunit of NMDA receptor is a long lasting result of chronic opioid abuse. PMID: 20153313
- These observations suggest that the genetic variation of the NR3B subunit of the NMDA receptor is not a risk factor for Alzheimer's dis pathogenesis PMID: 20016182
- NR3B mRNA expression in the human hippocampal formation (CA1-CA4 and dentate gyrus) and adjacent neocortex may have implications for understanding the role of NMDA receptors for physiological and pathological processes in these forebrain regions. PMID: 15722182
- cross-talk between NR3B and NR4A receptors is a mechanism modulating the transcriptional activities of these orphan nuclear receptors PMID: 17543277
- We tested whether genetic dysfunction of GRIN3B is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). PMID: 17687115
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亞細(xì)胞定位:Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.
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蛋白家族:Glutamate-gated ion channel (TC 1.A.10.1) family, NR3B/GRIN3B subfamily
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數(shù)據(jù)庫鏈接:
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