FEN1 Antibody
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中文名稱:FEN1兔多克隆抗體
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貨號:CSB-PA008585XA01DOA
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
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別名:Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) FEN1 At5g26680 F21E10.3
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反應種屬:Drosophila melanogaster (Fruit fly)
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免疫原:Recombinant Arabidopsis thaliana FEN1 protein
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免疫原種屬:Arabidopsis thaliana (Mouse-ear cress)
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標記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Protein G
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式:Liquid
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應用范圍:ELISA, WB
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點詳情
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功能:Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
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基因功能參考文獻:
- At5g26680 role in mediating transcriptional gene silencing as well as maintaining genome stability PMID: 27231839
- Data show that shade avoidance 6 (SAV6; At5g26680), encodes flap endonuclease-1 (FEN1), assures proper root development through maintenance of genome integrity. PMID: 26721386
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亞細胞定位:Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion.
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蛋白家族:XPG/RAD2 endonuclease family, FEN1 subfamily
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數(shù)據(jù)庫鏈接:
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