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CRHR1 Antibody

  • 中文名稱：
    CRHR1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA001787
  • 規(guī)格：
    ￥880
  • 圖片：
    • Western Blot analysis of LOVO cells using CRF-RI Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Corticotropin releasing factor type 1 receptor antibody; corticotropin releasing hormone receptor 1 antibody; Corticotropin-releasing factor receptor 1 antibody; Corticotropin-releasing hormone receptor 1 antibody; CRF R antibody; crf receptor 1 antibody; crf receptor type 1 antibody; crf type 1 antibody; CRF-R antibody; CRF-R-1 antibody; CRF-R1 antibody; CRF1 antibody; CRFR antibody; CRFR-1 antibody; CRFR1 antibody; CRFR1_HUMAN antibody; CRH-R-1 antibody; CRH-R1 antibody; CRH-R1h antibody; CRHR antibody; Crhr1 antibody; CRHR1f antibody; CRHR1L antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CRF-RI.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 組織特異性：
    Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2357

    OMIM: 122561

    KEGG: hsa:104909134

    STRING: 9606.ENSP00000381333

    UniGene: Hs.417628