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Rat anti-Mullerian hormone (AMH) ELISA kit

  • 中文名稱:
    大鼠繆勒管抑制物質/抗繆勒管激素(AMH)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-E11162r
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 其他:

產品詳情

  • 產品描述:
        AMH(抗Müllerian激素,anti-Müllerian hormone)是一種由睪丸和卵巢分泌的蛋白質,對生殖器的發(fā)育和成熟有重要作用。在男性中,AMH促進睪丸的發(fā)育,調節(jié)睪丸的分泌和精子的發(fā)生;在女性中,AMH則調節(jié)卵巢的發(fā)育和排卵過程。AMH的水平可以作為評估卵巢功能和生育能力的指標之一,對不孕不育的診斷和治療具有重要意義。
        華美生物所提供的Rat anti-Mullerian hormone (AMH) ELISA kit屬于ELISA檢測試劑盒,采用競爭法定量檢測大鼠血清、血漿、組織勻漿樣本中的AMH,其靈敏度為0.1 ng/mL,檢測范圍為0.2 ng/mL-15 ng/mL。
     
  • 別名:
    Amh ELISA Kit; Muellerian-inhibiting factor ELISA Kit; Anti-Muellerian hormone ELISA Kit; AMH ELISA Kit; Muellerian-inhibiting substance ELISA Kit; MIS ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    0.2 ng/mL-15 ng/mL
  • 靈敏度:
    0.1 ng/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Signal Transduction
  • 測定原理:
    quantitative
  • 測定方法:
    Competitive
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

引用文獻

產品評價

靶點詳情

  • 最新研究進展:
    AMH是一種由生殖細胞產生的生長因子,主要參與了性腺的發(fā)育和生殖調節(jié)。最新研究表明,AMH在女性中發(fā)揮著重要的作用,如參與卵巢生長和發(fā)育、卵泡發(fā)育和成熟、排卵和孕產等過程。此外,AMH在生殖醫(yī)學中也被廣泛應用于卵巢儲備功能評估和IVF治療等方面。近年來,一些新型AMH檢測技術的研究也為AMH在臨床上的應用提供了更加準確和可靠的方法。
  • 功能:
    This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
  • 基因功能參考文獻:
    1. The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
    2. AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
    3. Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
    4. AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
    5. In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688
    6. Mullerian inhibiting substance regulates gonadotropin gene expression PMID: 12878721
    7. MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID: 14585814

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  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    TGF-beta family
  • 數(shù)據(jù)庫鏈接: