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Human Serum amyloid A-4 protein(SAA4) ELISA kit

  • 中文名稱:
    人血清淀粉樣蛋白A4(SAA4)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-EL020659HU
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
        SAA4 (Serum amyloid A4) 是一種由SAA4基因編碼的蛋白質(zhì),屬于血清淀粉樣蛋白A(SAA)家族。SAA4的主要功能是作為一種炎癥蛋白參與炎癥反應(yīng)的調(diào)節(jié)。SAA4可以在肝臟和其他組織中被產(chǎn)生,其產(chǎn)生水平會受到多種因素的影響,如感染、腫瘤、創(chuàng)傷、糖尿病等。研究表明,SAA4在多種疾病的診斷和治療中可能具有潛在的臨床應(yīng)用價值。
        華美生物所提供的Human Serum amyloid A-4 protein(SAA4) ELISA kit屬于ELISA檢測試劑盒,采用雙抗夾心法定量檢測人血清、血漿、組織勻漿樣本中的SAA4,其靈敏度為3.9 ng/ml,檢測范圍為15.6 ng/ml-1000 ng/ml。
     
  • 別名:
    Amyloid A; serum; 4 ELISA Kit; C SAA ELISA Kit; C-SAA ELISA Kit; Constitutively expressed serum amyloid A protein ELISA Kit; CSAA ELISA Kit; SAA 4 ELISA Kit; Saa4 ELISA Kit; SAA4 protein ELISA Kit; SAA4_HUMAN ELISA Kit; Serum amyloid A 4 protein ELISA Kit; Serum amyloid A-4 protein ELISA Kit; Serum amyloid A4 constitutive ELISA Kit
  • 縮寫:
    SAA4
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    15.6 ng/ml-1000 ng/ml.
  • 靈敏度:
    3.9 ng/ml.
  • 反應(yīng)時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領(lǐng)域:
    Cardiovascular
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 最新研究進(jìn)展:
    SAA4(serum amyloid A4)是SAA蛋白家族的一員,參與機體的免疫調(diào)節(jié)和炎癥反應(yīng)。最新研究表明,SAA4在某些腫瘤中表達(dá)升高,與腫瘤的發(fā)生和進(jìn)展密切相關(guān)。此外,SAA4也參與了許多炎癥和自身免疫疾病的發(fā)生和發(fā)展,成為新型治療策略的熱點研究對象。
  • 功能:
    Major acute phase reactant.
  • 基因功能參考文獻(xiàn):
    1. Data identified SAA4 as a protein that was positively correlated with RF and RA. SAA4 may represent a novel prescreening marker for the diagnosis of RA. PMID: 28505104
    2. expressed in invasive trophoblast cells PMID: 24951172
    3. Six apolipoproteins (APOA1, APOA2, APOB, APOC2, APOC3, and APOE) were able to differentiate bladder cancer from hernia. SAA4 was significantly increased in bladder cancer subgroups, whereas ProEGF was significantly decreased in bladder cancer subgroups. PMID: 23631828
    4. studies provide the first evidence for a novel type of AA amyloidosis in which the fibrils were formed from a mutated SAA4 protein PMID: 20536400
    5. The sequences of 1478 and 1836 bp of the SAA1 and SAA4 5'-flanking regions were determined. PMID: 12410800

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  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    SAA family
  • 組織特異性:
    Expressed by the liver; secreted in plasma.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10516

    OMIM: 104752

    KEGG: hsa:6291

    STRING: 9606.ENSP00000278222

    UniGene: Hs.1955