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RNF43

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity).

RNF43 Antibodies

RNF43 for Homo sapiens (Human)

RNF43 Proteins

RNF43 Proteins for Homo sapiens (Human)

RNF43 Proteins for Mus musculus (Mouse)