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MRE11

Double-strand break repair protein MRE11 is a protein in humans that is encoded by MRE11 gene. Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11 to prevent nucleolytic degradation past a given point.

MRE11 Antibodies

MRE11 for Homo sapiens (Human)

MRE11 Proteins

MRE11 Proteins for Homo sapiens (Human)

MRE11 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

MRE11 Proteins for Nanoarchaeum equitans (strain Kin4-M)

MRE11 Proteins for Methanococcus maripaludis (strain S2 / LL)

MRE11 Proteins for Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)

MRE11 Proteins for Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum)

MRE11 Proteins for Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

MRE11 Proteins for Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

MRE11 Proteins for Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)

MRE11 Proteins for Mus musculus (Mouse)

MRE11 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

MRE11 Proteins for Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)

MRE11 Proteins for Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)

MRE11 Proteins for Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

MRE11 Proteins for Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)

MRE11 Proteins for Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

MRE11 Proteins for Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

MRE11 Proteins for Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)

MRE11 Proteins for Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)

MRE11 Proteins for Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)

MRE11 Proteins for Rattus norvegicus (Rat)

MRE11 Proteins for Gallus gallus (Chicken)

MRE11 Proteins for Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

MRE11 Proteins for Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)

MRE11 Proteins for Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)

MRE11 Proteins for Pyrococcus abyssi (strain GE5 / Orsay)

MRE11 Proteins for Xenopus laevis (African clawed frog)

MRE11 Proteins for Arabidopsis thaliana (Mouse-ear cress)