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IL10

IL10,即白介素10,別名人類細(xì)胞因子SYNERGY1、CGF-1等。它是一種由IL10基因編碼的細(xì)胞因子,主要由Th2細(xì)胞、單核細(xì)胞、巨噬細(xì)胞等免疫細(xì)胞產(chǎn)生。IL10的作用機(jī)制主要是通過(guò)與其受體IL10R結(jié)合,激活JAK/STAT信號(hào)通路,抑制促炎細(xì)胞因子的產(chǎn)生,調(diào)節(jié)免疫細(xì)胞的活性,維持免疫平衡。IL10的意義非常廣泛,它參與了抗炎反應(yīng)、免疫調(diào)節(jié)、細(xì)胞增殖和凋亡等過(guò)程,對(duì)抑制過(guò)度的免疫反應(yīng)、防止自身免疫性疾病和促進(jìn)組織修復(fù)具有重要作用。IL10的異常表達(dá)與多種疾病有關(guān),包括癌癥、炎癥性腸病和自身免疫性疾病,是免疫學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Interleukin-10 (IL10) (CSB-MP011580HUc7)

驗(yàn)證數(shù)據(jù)

CSB-MP011580HUc7

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL10 Recombinant Monoclonal Antibody (CSB-RA011580MA1HU)

驗(yàn)證數(shù)據(jù)

CSB-RA011580MA1HU

IHC image of CSB-RA011580MA1HU diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Human IgG labeled by HRP and visualized using 0.05% DAB.

IL10 Antibodies

IL10 for Homo sapiens (Human)

IL10 for Bovine

IL10 for Macaca mulatta

IL10 Proteins

IL10 Proteins for Mus musculus (Mouse)

IL10 Proteins for Homo sapiens (Human)

IL10 Proteins for Bos taurus (Bovine)

IL10 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

IL10 Proteins for Macaca mulatta (Rhesus macaque)

IL10 Proteins for Felis catus (Cat) (Felis silvestris catus)

IL10 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

IL10 Proteins for Rattus norvegicus (Rat)

IL10 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)

IL10 Proteins for Cervus elaphus (Red deer)

IL10 Proteins for Macaca nemestrina (Pig-tailed macaque)

IL10 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

IL10 Proteins for Pan troglodytes (Chimpanzee)

IL10 Proteins for Trichosurus vulpecula (Brush-tailed possum)

IL10 Proteins for Orcinus orca (Killer whale)

IL10 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

IL10 Proteins for Equus caballus (Horse)

IL10 Proteins for Vulpes vulpes (Red fox)

IL10 Proteins for Sus scrofa (Pig)

IL10 Proteins for Ovis aries (Sheep)

IL10 Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

IL10 Proteins for Gallus gallus (Chicken)

IL10 Proteins for Papio hamadryas (Hamadryas baboon)

IL10 Proteins for Lama glama (Llama)

IL10 Proteins for Saimiri sciureus (Common squirrel monkey)

IL10 Proteins for Oryctolagus cuniculus (Rabbit)

IL10 Proteins for Marmota monax (Woodchuck)

IL10 ELISA Kit

IL10 ELISA Kit for Bos taurus (Bovine)

IL10 ELISA Kit for Gallus gallus (Chicken)

IL10 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

IL10 ELISA Kit for Guinea Sus scrofa (Pig)

IL10 ELISA Kit for Homo sapiens (Human)

IL10 ELISA Kit for Mus musculus (Mouse)

IL10 ELISA Kit for Sus scrofa (Pig)

IL10 ELISA Kit for Oryctolagus cuniculus (Rabbit)

IL10 ELISA Kit for Rattus norvegicus (Rat)

IL10 ELISA Kit for Ovis aries (Sheep)