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FUT3

FUT3,即巖藻糖基轉(zhuǎn)移酶3,別名Fucosyltransferase 3、Fuc-T III等。它是一種由FUT3基因編碼的酶,屬于糖基轉(zhuǎn)移酶家族成員,在多種細(xì)胞類型中表達(dá)。FUT3的作用機(jī)制涉及催化巖藻糖從GDP-巖藻糖轉(zhuǎn)移到糖蛋白或糖脂的特定糖基受體上,參與糖基化過程,對(duì)細(xì)胞表面分子的功能和穩(wěn)定性具有重要影響。FUT3參與了細(xì)胞識(shí)別、信號(hào)傳導(dǎo)、細(xì)胞黏附和免疫反應(yīng)等多種生理過程。FUT3的活性對(duì)于維持細(xì)胞表面分子的正常功能至關(guān)重要,其異常表達(dá)或功能失調(diào)可能與某些疾病有關(guān),例如在某些類型的癌癥中,F(xiàn)UT3的表達(dá)水平可能與腫瘤的侵襲性和轉(zhuǎn)移能力有關(guān)。FUT3是細(xì)胞生物學(xué)和疾病治療研究中的一個(gè)潛在靶點(diǎn)。

熱銷產(chǎn)品

FUT3 Antibody (CSB-PA009077LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA009077LA01HU

Western Blot
Positive WB detected in: Rat lung tissue
All lanes: FUT3 antibody at 5.3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa

CSB-PA009077LA01HU

IHC image of CSB-PA009077LA01HU diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

FUT3 Antibodies

FUT3 for Homo sapiens (Human)

FUT3 Proteins

FUT3 Proteins for Homo sapiens (Human)

FUT3 Proteins for Pan troglodytes (Chimpanzee)

FUT3 Proteins for Bos taurus (Bovine)

FUT3 Proteins for Pongo pygmaeus (Bornean orangutan)

FUT3 Proteins for Arabidopsis thaliana (Mouse-ear cress)