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DERL3

Derlin-3 is a protein in humans that is encoded by DERL3 gene. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded glycoproteins.

DERL3 Proteins

DERL3 Proteins for Bos taurus (Bovine)

DERL3 Proteins for Homo sapiens (Human)

DERL3 Proteins for Mus musculus (Mouse)