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ARF1

ADP-ribosylation factor 1is a protein in humans that is encoded by ARF1 gene. GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity.

ARF1 Antibodies

ARF1 for Homo sapiens (Human)

ARF1 Proteins

ARF1 Proteins for Homo sapiens (Human)

ARF1 Proteins for Rattus norvegicus (Rat)

ARF1 Proteins for Mus musculus (Mouse)

ARF1 Proteins for Bos taurus (Bovine)

ARF1 Proteins for Catharanthus roseus (Madagascar periwinkle) (Vinca rosea)

ARF1 Proteins for Salix bakko (Japanese willow)

ARF1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

ARF1 Proteins for Arabidopsis thaliana (Mouse-ear cress)

ARF1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

ARF1 Proteins for Xenopus laevis (African clawed frog)

ARF1 Proteins for Daucus carota (Carrot)

ARF1 Proteins for Chlamydomonas reinhardtii (Chlamydomonas smithii)

ARF1 Proteins for Locusta migratoria (Migratory locust)

ARF1 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

ARF1 Proteins for Zea mays (Maize)

ARF1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

ARF1 Proteins for Plasmodium falciparum (isolate 3D7)

ARF1 Proteins for Plasmodium falciparum

ARF1 Proteins for Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)

ARF1 Proteins for Plasmodium falciparum (isolate NF54)

ARF1 Proteins for Oryza sativa subsp. japonica (Rice)

ARF1 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)